国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2011年
2期
136-138
,共3页
微RNAs%肺肿瘤%早期诊断%治疗应用%let-7 microRNA
微RNAs%肺腫瘤%早期診斷%治療應用%let-7 microRNA
미RNAs%폐종류%조기진단%치료응용%let-7 microRNA
MircoRNAs%Lung neoplasms%Early diagnosis%Therapeutic uses%Let-7 microRNA
肺癌中let-7表达普遍降低,而多种癌基因表达升高.导入let-7对肺癌细胞生长有明显的抑制作用.let-7有可能成为很好的靶点或者强有力的介入工具,将有望应用于肺癌的早期诊断、预后判断及治疗.
肺癌中let-7錶達普遍降低,而多種癌基因錶達升高.導入let-7對肺癌細胞生長有明顯的抑製作用.let-7有可能成為很好的靶點或者彊有力的介入工具,將有望應用于肺癌的早期診斷、預後判斷及治療.
폐암중let-7표체보편강저,이다충암기인표체승고.도입let-7대폐암세포생장유명현적억제작용.let-7유가능성위흔호적파점혹자강유력적개입공구,장유망응용우폐암적조기진단、예후판단급치료.
Let-7 is found to be downregulated in lung cancer while many kinds of oncogenes expression always increase, and restoration of the let-7 to normal expression level inhibits lung cancer growth evidently.Thus, let-7 might serves as good targets or effective interference tools in exploration of anticancer therapeutics,and has a good prospect in applying it in the early diagnosis, prognosis and therapy in lung cancer.
