CAJ | 학술논문

Rho/Rho激酶信号通路是真核细胞内广泛存在的一条信号通路,参与多种生物学行为.研究表明,Rho/Rho激酶在胰腺腺泡细胞、导管细胞及内分泌细胞均见表达,并与胰腺内、外分泌功能以及胰腺癌、胰腺炎和糖尿病的发生、发展密切相关.
Rho/Rho격매신호통로시진핵세포내엄범존재적일조신호통로,삼여다충생물학행위.연구표명,Rho/Rho격매재이선선포세포、도관세포급내분비세포균견표체,병여이선내、외분비공능이급이선암、이선염화당뇨병적발생、발전밀절상관.
Rho/Rho-kinase signaling pathway is a ubiquitous one in eukaryotic cells and plays a part in various biologic behaviors.Studies showed that it was expressed in pancreatic acinar,ductal and endocrine cells,as well as related to the pancreatic endocrine and exocrine functions.Moreover,the evidence showed that there was a close relationship the pathway and pancreatic cancer,pancreatitis,diabetes mellitus.