中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2009年
11期
31-33
,共3页
封凯旋%俞国忠%顾斌芳%凌杰兵%姜凯%瞿晓英%马斌
封凱鏇%俞國忠%顧斌芳%凌傑兵%薑凱%瞿曉英%馬斌
봉개선%유국충%고빈방%릉걸병%강개%구효영%마빈
机械通气%肺部感染%重症监护病房%危险因素%Logistic回归分析
機械通氣%肺部感染%重癥鑑護病房%危險因素%Logistic迴歸分析
궤계통기%폐부감염%중증감호병방%위험인소%Logistic회귀분석
Mechanical ventilation%Pulmonary infection%Intensive care unit%Risk factors%Logistic regression analysis
目的 探讨综合重症监护病房(ICU)机械通气并发肺部感染的独立危险因素.方法 对我院2006年10月至2008年6月入住综合ICU行有创机械通气的患者80例进行前瞻性队列研究,根据是否发生肺部感染,先用单因素分析筛选有统计学意叉的危险因素,再通过多元Logistic回归分析,确定机械通气并发肺部感染的独立危险因素.结果 本组患者肺部感染发生率为47.50%.单因素分析提示年龄、低蛋白血症、慢性阻塞性肺疾病(COPD)史、机械通气时间、多种抗生素的应用、ICU住院天数是肺部感染的危险因素,回归分析提示机械通气时间和多种抗生素的应用的相对危险度及其95%可信区间分别为1.257(1.004～3.587)、P=0.024,6.243(4.013～39.525)、P=0.007.结论 肺部感染的发生与多种临床因素相关,机械通气时间和多种抗生素的应用是肺部感染的独立危险因素.
目的 探討綜閤重癥鑑護病房(ICU)機械通氣併髮肺部感染的獨立危險因素.方法 對我院2006年10月至2008年6月入住綜閤ICU行有創機械通氣的患者80例進行前瞻性隊列研究,根據是否髮生肺部感染,先用單因素分析篩選有統計學意扠的危險因素,再通過多元Logistic迴歸分析,確定機械通氣併髮肺部感染的獨立危險因素.結果 本組患者肺部感染髮生率為47.50%.單因素分析提示年齡、低蛋白血癥、慢性阻塞性肺疾病(COPD)史、機械通氣時間、多種抗生素的應用、ICU住院天數是肺部感染的危險因素,迴歸分析提示機械通氣時間和多種抗生素的應用的相對危險度及其95%可信區間分彆為1.257(1.004～3.587)、P=0.024,6.243(4.013～39.525)、P=0.007.結論 肺部感染的髮生與多種臨床因素相關,機械通氣時間和多種抗生素的應用是肺部感染的獨立危險因素.
목적 탐토종합중증감호병방(ICU)궤계통기병발폐부감염적독립위험인소.방법 대아원2006년10월지2008년6월입주종합ICU행유창궤계통기적환자80례진행전첨성대렬연구,근거시부발생폐부감염,선용단인소분석사선유통계학의차적위험인소,재통과다원Logistic회귀분석,학정궤계통기병발폐부감염적독립위험인소.결과 본조환자폐부감염발생솔위47.50%.단인소분석제시년령、저단백혈증、만성조새성폐질병(COPD)사、궤계통기시간、다충항생소적응용、ICU주원천수시폐부감염적위험인소,회귀분석제시궤계통기시간화다충항생소적응용적상대위험도급기95%가신구간분별위1.257(1.004～3.587)、P=0.024,6.243(4.013～39.525)、P=0.007.결론 폐부감염적발생여다충림상인소상관,궤계통기시간화다충항생소적응용시폐부감염적독립위험인소.
Objective To explore independent risk factors of ventilator-associated hospital acquired pulmonary infection in comprehensive ICU.Methods A prospective cohort study was made on patients with mechanical ventilation were hospitalized from October 2006 to June 2008.Several statistically significant risk factors were screened out with univariate analysis,then independent risk factors were determined with multivariate stepwise logistic regression analysis.Results The morbidity of ventilatorassociated hospital acquired pulmonary infection was 47.50% in this groups.Univariate analysis showed that age,hypoalbuminemia,history of chronic obstructive pulmonary emphysema,the duration of mechanical ventilation,the use of various antibiotics and the length of stay in ICU were statistically significant risk factors of pulmonary infection.While multivariate stepwise logistic regression analysis showed that the relative risk and 95% confident interval of the duration of mechanical ventilation,the use of various antibiotics were respectively 1.257 (1.004-3.587),P = 0.024;6.243 (4.013-39.525),P = 0.007.Conclusions The occurrence of ventilator-associated hospital acquired pulmonary infection is related to multiple clinical factors.The duration of mechanical ventilation and the use of various antibiotics are independent and significant risk factors of ventilator-associated hospital acquired pulmonary infection.
