CAJ | 학술논문

MicroRNA(miRNA)是一类新型的调控基因表达的小分子RNA,它作为基因表达的负调控因子,在转录后水平调节靶基因的表达.miRNA参与调控植物的生长发育,并在多种非生物与生物胁迫响应中发挥重要作用.miR398是第一个被报道的受氧化胁迫负调控的miRNA.它通过负调控其靶基因Cu/Zn过氧化物歧化酶(Cu/Zn-superoxide dismutase,CSD)的表达,在多种逆境胁迫响应中扮演重要角色,如调节铜代谢平衡,应答重金属、蔗糖、臭氧等非生物胁迫,以及参与应答生物胁迫等.文章综述了miR398在多种逆境胁迫响应中重要的调节作用及miR398自身的转录调控.
MicroRNA(miRNA)시일류신형적조공기인표체적소분자RNA,타작위기인표체적부조공인자,재전록후수평조절파기인적표체.miRNA삼여조공식물적생장발육,병재다충비생물여생물협박향응중발휘중요작용.miR398시제일개피보도적수양화협박부조공적miRNA.타통과부조공기파기인Cu/Zn과양화물기화매(Cu/Zn-superoxide dismutase,CSD)적표체,재다충역경협박향응중분연중요각색,여조절동대사평형,응답중금속、자당、취양등비생물협박,이급삼여응답생물협박등.문장종술료miR398재다충역경협박향응중중요적조절작용급miR398자신적전록조공.
MicroRNAs(miRNAs)are a new class of small RNAs,which act as post-wanscriptional negative regulators of gene expression.Plant miRNAs are important in the regulation of plant growth,development and in response to various abiotic and biotic stresses.miR398 is the first reported miRNA to be down-regulated by oxidative stresses.miR398 plays an important role in stresses,such as regulating copper homeostasis,in response to abiotic stresses including heavy metals,sucrose,and ozone and biotic stresses via down-regulating the expression of Cu/Zn-superoxide dismutase(CSD).This review focused on the crucial role of miR398 in regulation of different stresses and the transcriptional regulation of MIR398gene.