国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2012年
3期
178-181
,共4页
林伟青%李伟中%林佩贤%辜红妮
林偉青%李偉中%林珮賢%辜紅妮
림위청%리위중%림패현%고홍니
细菌%儿科%耐药性
細菌%兒科%耐藥性
세균%인과%내약성
Bacteria%Pediatrics%Drug resistance
目的 了解儿科病区不发酵革兰阴性杆菌的检出及其耐药情况,为临床合理使用抗菌药物提供依据.方法 对儿科病区2009年1月至2011年6月的临床样本中分离培养的不发酵革兰阴性杆菌的分布及耐药情况进行调查分析,依据《全国临床检验操作规程》的规定要求分离培养病原菌,采用VITEKAMS微生物自动分析仪进行菌株鉴定.结果 在此期间,所检样本中共检出革兰阴性菌720株,其中不发酵革兰阴性杆菌232株,占革兰阴性菌的32.22％.检出数量居前3位病原菌依次为:鲍曼不动杆菌、铜绿假单孢菌、嗜麦芽寡养单胞菌,构成比分别为37.93％(88株)、36.21％(84株)、12.07％(28株),不发酵革兰阴性杆菌主要来源于痰样本(63.00％,126份)、胃液(15.00％,30份)和血液(14.00％,28份),耐药率较高.结论 通过病原体监测了解细菌分布及其耐药趋势,对合理选择抗菌药物,控制耐药菌株产生,有效治疗和预防不发酵革兰阴性杆菌引起的感染性疾病有重要意义.
目的 瞭解兒科病區不髮酵革蘭陰性桿菌的檢齣及其耐藥情況,為臨床閤理使用抗菌藥物提供依據.方法 對兒科病區2009年1月至2011年6月的臨床樣本中分離培養的不髮酵革蘭陰性桿菌的分佈及耐藥情況進行調查分析,依據《全國臨床檢驗操作規程》的規定要求分離培養病原菌,採用VITEKAMS微生物自動分析儀進行菌株鑒定.結果 在此期間,所檢樣本中共檢齣革蘭陰性菌720株,其中不髮酵革蘭陰性桿菌232株,佔革蘭陰性菌的32.22％.檢齣數量居前3位病原菌依次為:鮑曼不動桿菌、銅綠假單孢菌、嗜麥芽寡養單胞菌,構成比分彆為37.93％(88株)、36.21％(84株)、12.07％(28株),不髮酵革蘭陰性桿菌主要來源于痰樣本(63.00％,126份)、胃液(15.00％,30份)和血液(14.00％,28份),耐藥率較高.結論 通過病原體鑑測瞭解細菌分佈及其耐藥趨勢,對閤理選擇抗菌藥物,控製耐藥菌株產生,有效治療和預防不髮酵革蘭陰性桿菌引起的感染性疾病有重要意義.
목적 료해인과병구불발효혁란음성간균적검출급기내약정황,위림상합리사용항균약물제공의거.방법 대인과병구2009년1월지2011년6월적림상양본중분리배양적불발효혁란음성간균적분포급내약정황진행조사분석,의거《전국림상검험조작규정》적규정요구분리배양병원균,채용VITEKAMS미생물자동분석의진행균주감정.결과 재차기간,소검양본중공검출혁란음성균720주,기중불발효혁란음성간균232주,점혁란음성균적32.22％.검출수량거전3위병원균의차위:포만불동간균、동록가단포균、기맥아과양단포균,구성비분별위37.93％(88주)、36.21％(84주)、12.07％(28주),불발효혁란음성간균주요래원우담양본(63.00％,126빈)、위액(15.00％,30빈)화혈액(14.00％,28빈),내약솔교고.결론 통과병원체감측료해세균분포급기내약추세,대합리선택항균약물,공제내약균주산생,유효치료화예방불발효혁란음성간균인기적감염성질병유중요의의.
Objective To investigate the clinical distribution characteristics and drug resistances of non-fermentative gram-negative bacillus in pediatric ward,so as to direct rational antibacterial agents application.Methods A retrospective investigation was made for the clinical pathogens as well as the drug resistance in pediatric ward from January 2009 to June 2011.The bacteria were isolated according to National Clinical Laboratory Opiating Procedure.VITEKAMS automatic analyzer was applied for microbial strain identification.Results During the period,720 strains of gramnegative bacteria were isolated in all the detecting samples.Among them,there were 232 strains of non-fenmentative gram-negative bacillus,which accounted for 32.22％ of gram-negative bacteria.The top 3 pathogens were Pseudomonas aeruginosa,Acinetobacter baumannii and Stenorophomonas maltophilia,accounted for 37.93％(88 strains),36.21％ (84 strains),12.07％(28 strains),respectively.Non-fermentative gram -negative bacillus were mainly separated from sputum(63.00％,126 samples),stomach fluid(15.00％,30 samples) and blood(14.00％,28 samples) and the rates of drug resistance were noteworthy.Conclusions It is important to inspect patbogens and study the trend of drug resistance for selecting antibiotics rationally,reduce infection incidence and treat infection effectively caused by non-fermentative gram-negative bacillus,and decrease the occurence of drug resistant strains in pediatric ward.
