中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
16期
26-27
,共2页
危重病%乳酸%急性病生理学和长期健康评价
危重病%乳痠%急性病生理學和長期健康評價
위중병%유산%급성병생이학화장기건강평개
Critical illness%Lactic acid%APACHE
目的 探讨危重病患者动脉血乳酸水平与急性生理学及慢性健康状况评分Ⅱ(APACHEⅡ)之间的关系.方法 选择危重病患者71例,根据预后将患者分为死亡组16例和存活组55例,分析两组患者入院24 h内动脉血乳酸水平与APACHE Ⅱ及预后之间的关系.结果 随着APACHEⅡ的增加,动脉血乳酸水平和病死率均显著升高,APACHEⅡ>30分时,血乳酸水平已达(8.20±3.52)mmol/L,病死率则为64.7%(11/17),各分值之间比较差异均有统计学意义(P＜0.05).直线相关分析显示:动脉血乳酸水平与APACHEⅡ呈显著正相关(r=0.563,P<005).死亡组的APACHEⅡ和动脉血乳酸水平分别为(29.7±6.9)分和(7.6±4.1)mmol/L,均显著高于存活组的(18.3±7.0)分和(3.0±1.7)mmol/L,差异有统计学意义(P＜0.05).结论 危重病患者动脉血乳酸水平与 APACHEⅡ呈正相关关系,其水平对于判断危重病患者病情的严重程度和预后有重要临床意义.
目的 探討危重病患者動脈血乳痠水平與急性生理學及慢性健康狀況評分Ⅱ(APACHEⅡ)之間的關繫.方法 選擇危重病患者71例,根據預後將患者分為死亡組16例和存活組55例,分析兩組患者入院24 h內動脈血乳痠水平與APACHE Ⅱ及預後之間的關繫.結果 隨著APACHEⅡ的增加,動脈血乳痠水平和病死率均顯著升高,APACHEⅡ>30分時,血乳痠水平已達(8.20±3.52)mmol/L,病死率則為64.7%(11/17),各分值之間比較差異均有統計學意義(P＜0.05).直線相關分析顯示:動脈血乳痠水平與APACHEⅡ呈顯著正相關(r=0.563,P<005).死亡組的APACHEⅡ和動脈血乳痠水平分彆為(29.7±6.9)分和(7.6±4.1)mmol/L,均顯著高于存活組的(18.3±7.0)分和(3.0±1.7)mmol/L,差異有統計學意義(P＜0.05).結論 危重病患者動脈血乳痠水平與 APACHEⅡ呈正相關關繫,其水平對于判斷危重病患者病情的嚴重程度和預後有重要臨床意義.
목적 탐토위중병환자동맥혈유산수평여급성생이학급만성건강상황평분Ⅱ(APACHEⅡ)지간적관계.방법 선택위중병환자71례,근거예후장환자분위사망조16례화존활조55례,분석량조환자입원24 h내동맥혈유산수평여APACHE Ⅱ급예후지간적관계.결과 수착APACHEⅡ적증가,동맥혈유산수평화병사솔균현저승고,APACHEⅡ>30분시,혈유산수평이체(8.20±3.52)mmol/L,병사솔칙위64.7%(11/17),각분치지간비교차이균유통계학의의(P＜0.05).직선상관분석현시:동맥혈유산수평여APACHEⅡ정현저정상관(r=0.563,P<005).사망조적APACHEⅡ화동맥혈유산수평분별위(29.7±6.9)분화(7.6±4.1)mmol/L,균현저고우존활조적(18.3±7.0)분화(3.0±1.7)mmol/L,차이유통계학의의(P＜0.05).결론 위중병환자동맥혈유산수평여 APACHEⅡ정정상관관계,기수평대우판단위중병환자병정적엄중정도화예후유중요림상의의.
Objective To investigate the correlation between arterial blood lactate levels and acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) in critically ill patients.Methods Seventy-one patients with critical illness who treated in intensive care unit were included as research subjects and divided into death group with 16 cases and survival group with 55 cases according to the prognosis.The correlation between arterial blood lactate levels and APACHE Ⅱ was analyzed.Results With the increase of APACHE Ⅱ ,arterial blood lactate levels and mortality all increased significantly.The blood lactate levels reached (8.20±3.52) mmol/L and mortality was 64.7%(11/17) when APACHE Ⅱ >30 scores,and there were significant differences between different segment of APACHE Ⅱ (P <0.05).Linear correlation analysis showed:arterial blood lactate levels were positively correlated to APACHE Ⅱ significantly (r = 0.563,P <0.05).The APACHE Ⅱ and arterial blood lactate levels in the death group were (29.7 ± 6.9) scores and (7.6 ±4.1) mmol/L respectively,which were significantly higher than those in the survival group [(18.3 ± 7.0) scores and(3.0 ± 1.7) mmol/L].The differences between two groups were statistically significant (P＜0.05).Conclusion The arterial blood lactate levels of critically ill patients are positively related to APACHE Ⅱ ,and its level has an important clinical significance in judging the severity and the prognosis of the illness.
