CAJ | 학술논문

背景流行病学调查结果显示,不同民族结膜囊的菌种分布有所不同,可能与其居住环境有关.了解不同民族结膜囊菌种的分布特点对感染性眼病的防治具有重要意义.目的了解藏族与汉族中老年人结膜囊细菌状况的异同.方法整群抽取四川甘孜州康定县、九龙县各1个藏族聚居地40岁以上藏族人群145人,九龙县1个及康定县2个汉族聚居地汉族人群173人,共计346眼进行调查,取结膜囊分泌物进行细菌培养及分离鉴定,比较藏族与汉族人群的检查结果.结果受试的藏族和汉族人群的性别及年龄的差异均无统计学意义(x2=0.987,P=0.320;t=1.142,P=0.254),两组人群农牧民和非农业人口构成比的差异有统计学意义(x2=8.557,p=0.000).藏族人群结膜囊细菌培养阳性率为50.7％,汉族为60.4％,藏族人群结膜囊细菌培养阳性率低于汉族,差异有统计学意义(x2 =6.042,P=0.014).藏族结膜囊多种细菌共存者占11.6％,汉族为11.0％,差异无统计学意义(x2=0.027,P=0.869);藏族人群结膜囊中表皮葡萄球菌培养的阳性率为26.6％,汉族人群为33.2％,差异无统计学意义(x2=3.350,P=0.060)；藏族人群结膜囊内棒状杆菌培养的阳性率为15.9％,汉族人群为17.3％；差异无统计学意义(x2=0.248,P=0.618).结论四川甘孜州藏区藏族中老年人结膜囊细菌培养阳性率较汉族中老年人低,藏族和汉族中老年人结膜囊的细菌的种类及分布相似.
배경 류행병학조사결과현시,불동민족결막낭적균충분포유소불동,가능여기거주배경유관.료해불동민족결막낭균충적분포특점대감염성안병적방치구유중요의의.목적 료해장족여한족중노년인결막낭세균상황적이동.방법 정군추취사천감자주강정현、구룡현각1개장족취거지40세이상장족인군145인,구룡현1개급강정현2개한족취거지한족인군173인,공계346안진행조사,취결막낭분비물진행세균배양급분리감정,비교장족여한족인군적검사결과.결과 수시적장족화한족인군적성별급년령적차이균무통계학의의(x2=0.987,P=0.320;t=1.142,P=0.254),량조인군농목민화비농업인구구성비적차이유통계학의의(x2=8.557,p=0.000).장족인군결막낭세균배양양성솔위50.7％,한족위60.4％,장족인군결막낭세균배양양성솔저우한족,차이유통계학의의(x2 =6.042,P=0.014).장족결막낭다충세균공존자점11.6％,한족위11.0％,차이무통계학의의(x2=0.027,P=0.869);장족인군결막낭중표피포도구균배양적양성솔위26.6％,한족인군위33.2％,차이무통계학의의(x2=3.350,P=0.060)；장족인군결막낭내봉상간균배양적양성솔위15.9％,한족인군위17.3％；차이무통계학의의(x2=0.248,P=0.618).결론 사천감자주장구장족중노년인결막낭세균배양양성솔교한족중노년인저,장족화한족중노년인결막낭적세균적충류급분포상사.
Background Epidemiological surveys showed that the types of bacteria are different in the conjunvical sac from different nationalities,which possibly is associated with living environment.To characterize the types of conjunctival bacteria involved is important for the prevention and treatment of infectious eye diseases.Objective The present survey was to obtain data about bacterial species in the conjunctival sac in the Tibetan minority population aged over 40 years old and compared with the matched Han nationality population.Methods The standardized training and protocol were performed before this survey.A total of 290 eyes of 145 individuals from the Tibetan minority and 346 eyes of 173 subjects from the Han nationality were enrolled in this study in Ganzi Autonomous Prefecture,who had received questionnaire surveys and ophthalmological examinations.The secretion of the inferior palpebral conjunctival sac was embrocated and inoculated and grown on blood plates for 48-72 hours.The bacteria were isolated and identified.This study was approved by the Medical Ethic Committee of the Sichuan People Hospital.Oral informed consent was obtained from the subjects.Results No significant differences were seen in the constituent ratio of the gender as well as the age between the Tibetan minority and Han nationality in this study (x2 =0.987,P=0.3202;t=1.142,P=0.254).There was a significant difference in the proportions of farmers and herdsmen between the two groups(x2 =8.557,P =0.000).The positive rate of bacterial cultivation in Tibetan individuals was 50.74％,showing a statistically significant decrease in comparison with the Han people(60.4％)(x2=6.042,P=0.014).There was no statistical difference in the multiple bacterial species between the two groups (11.0％ in Tibetan,11.6％ in Han people)(x2 =0.0271,P =0.869).The rate of staphylococcus epidemics was 26.6％ in the Tibetan minority and that of Han population was 33.2％,without a significant difference between them (x2 =3.350,P=0.060).No significant difference was seen in the ratio of corynbacterium infection between the two population(15.9％ vs.17.3％)(x2 =0.248,P =0.618).Conclusions The ratio of bacterial cultivation in Tibetans is statistically lower than that of the Han people.The types and distribution of bacteria are similar in the Tibetan and Han nationality.