中华眼科杂志
中華眼科雜誌
중화안과잡지
Chinese Journal of Ophthalmology
2011年
9期
811-814
,共4页
眶肿瘤%内瘤,髓样%预后
眶腫瘤%內瘤,髓樣%預後
광종류%내류,수양%예후
Orbital neoplasms%Sarcoma,myeloid%Prognosis
目的 总结眼眶绿色瘤的临床表现、诊断方法及治疗原则。方法 回顾性系列病例研究。收集临床诊断为眼眶绿色瘤患者的病例资料17例，对其临床症状、眼部体征、影像学检查、诊断、治疗及预后进行分析。结果 眼眶绿色瘤好发于男性，多见于14岁以下青少年和儿童，多以眼球突出、眶区肿物就诊。B超检查16例，主要表现为位于眶外上和外下方的形状不规则肿物，边界清楚，呈低回声。彩色多普勒血流显像5例，主要表现为病变内丰富的红蓝血流信号。CT扫描11例，主要表现为位于外上或外下方、形状不规则、边界清楚肿物，密度均匀，少有骨破坏。实验室检查17例，多伴白细胞增高，血涂片可见大量幼稚细胞的血液系统改变。16例病例确诊后转儿科或血液科进行化疗，有随访资料者4例，其中2例3个月后死亡。结论 眼眶绿色瘤易误诊为横纹肌肉瘤等儿童时期眼眶恶性肿瘤，确诊需结合多种影像学检查及全身血液学检查，治疗以放、化疗为主。
目的 總結眼眶綠色瘤的臨床錶現、診斷方法及治療原則。方法 迴顧性繫列病例研究。收集臨床診斷為眼眶綠色瘤患者的病例資料17例，對其臨床癥狀、眼部體徵、影像學檢查、診斷、治療及預後進行分析。結果 眼眶綠色瘤好髮于男性，多見于14歲以下青少年和兒童，多以眼毬突齣、眶區腫物就診。B超檢查16例，主要錶現為位于眶外上和外下方的形狀不規則腫物，邊界清楚，呈低迴聲。綵色多普勒血流顯像5例，主要錶現為病變內豐富的紅藍血流信號。CT掃描11例，主要錶現為位于外上或外下方、形狀不規則、邊界清楚腫物，密度均勻，少有骨破壞。實驗室檢查17例，多伴白細胞增高，血塗片可見大量幼稚細胞的血液繫統改變。16例病例確診後轉兒科或血液科進行化療，有隨訪資料者4例，其中2例3箇月後死亡。結論 眼眶綠色瘤易誤診為橫紋肌肉瘤等兒童時期眼眶噁性腫瘤，確診需結閤多種影像學檢查及全身血液學檢查，治療以放、化療為主。
목적 총결안광록색류적림상표현、진단방법급치료원칙。방법 회고성계렬병례연구。수집림상진단위안광록색류환자적병례자료17례，대기림상증상、안부체정、영상학검사、진단、치료급예후진행분석。결과 안광록색류호발우남성，다견우14세이하청소년화인동，다이안구돌출、광구종물취진。B초검사16례，주요표현위위우광외상화외하방적형상불규칙종물，변계청초，정저회성。채색다보륵혈류현상5례，주요표현위병변내봉부적홍람혈류신호。CT소묘11례，주요표현위위우외상혹외하방、형상불규칙、변계청초종물，밀도균균，소유골파배。실험실검사17례，다반백세포증고，혈도편가견대량유치세포적혈액계통개변。16례병례학진후전인과혹혈액과진행화료，유수방자료자4례，기중2례3개월후사망。결론 안광록색류역오진위횡문기육류등인동시기안광악성종류，학진수결합다충영상학검사급전신혈액학검사，치료이방、화료위주。
Objective To analyze and summarize the clinical aspects, diagnostic methods and treatment principle of the orbit chloroma. Methods It was a retrospective case series study. The clinical aspects of 17 orbital chloroma cases were analyzed, which included symptoms, signs, imageology,diagnosis, treatment and prognosis. ResultsOrbit chlorona was more prevalent in males, and usually occurred in children and individuals under 14 years old. The main symptoms were exophthalmos and orbit masses. B ultrasonic examination was performed in 16 cases, which found that the mass was located in the temporal side of the orbit, with irregular shape and clear edge. Color doppler imaging was performed in 5 cases, which found that the sufficient blood supply signal was the main manifestation. CT scan was performed in 11 cases, which revealed that the mass was located in temporal side of the orbit, with irregular shape, regular density, a clear edge and seldom destruction of the orbital bone. Blood examination was performed in 17 cases, which revealed the increase of white blood cells and the presence of numerous immature blood cells. Sixteen cases were referred to the department of hematology for treatment. In 4 following cases, 2 cases were died within 3 months. ConclusionsOrbital chlorona can be easily misdiagnosed as other types of malignant orbital tumor in children. The diagnosis of orbital chloroma can be established by radiology and hematological examinations. This tumor can be treated by chemotherapy and radiotherapy.
