CAJ | 학술논문

目的探讨超声实时组织弹性成像技术定量评价甲状腺良恶性肿块的应用价值.方法对73例甲状腺肿块患者共95个病灶,应用实时组织弹性成像技术获得肿块应变率与胸锁乳突肌弹性应变率比值,判断病灶的良恶性,并与术后病理结果进行对照,绘制ROC曲线图,获得区分甲状腺肿块良恶性应变率比值的临界值.结果 ①甲状腺肿块良性组弹性应变率比值为2.06 ±1.01,恶性组弹性应变率比值为5.05 ±2.23,两组间差异有统计学意义(P＜0.05).②甲状腺良恶性肿块弹性应变率比值的ROC曲线下面积为0.929,差异有统计学意义(P＜0.05).③通过ROC曲线确定良、恶性肿块弹性应率比值的临界点为3.17,其灵敏度、特异度、阳性预测值、阴性预测值分别为96.7%、90.8%、93.3%和96.9%.结论超声实时组织弹性成像技术可以简便、无刨、定量地对甲状腺良、恶性肿块进行鉴别诊断.
목적 탐토초성실시조직탄성성상기술정량평개갑상선량악성종괴적응용개치.방법 대73례갑상선종괴환자공95개병조,응용실시조직탄성성상기술획득종괴응변솔여흉쇄유돌기탄성응변솔비치,판단병조적량악성,병여술후병리결과진행대조,회제ROC곡선도,획득구분갑상선종괴량악성응변솔비치적림계치.결과 ①갑상선종괴량성조탄성응변솔비치위2.06 ±1.01,악성조탄성응변솔비치위5.05 ±2.23,량조간차이유통계학의의(P＜0.05).②갑상선량악성종괴탄성응변솔비치적ROC곡선하면적위0.929,차이유통계학의의(P＜0.05).③통과ROC곡선학정량、악성종괴탄성응솔비치적림계점위3.17,기령민도、특이도、양성예측치、음성예측치분별위96.7%、90.8%、93.3%화96.9%.결론 초성실시조직탄성성상기술가이간편、무포、정량지대갑상선량、악성종괴진행감별진단.
Objective To evaluate the value of the real-time tissue elasticity imaging quantitative method in differential diagnosis of thyroid nodules.Methods Seventy-three patients with thyroid nodules，including 95 lesions,were included in the study.A total of thyroid nodules were examined with traditional ultrasonography and elastosonography from which the strain ratios(SR)were derived，with pathologic results as the reference standard.And a receiver-operating charaeterisitc(ROC)curve was used to identify the value of optimal operating point for differential diagnosis of thyroid nodules.Results ①The strain ratio of the benign lesions was 2.06 ±1.01，which was significantly different from the value of malignant lesions 5.05±2.23(P＜0.05).②The area under the curve was 0.929，which showed a high statistical significance.③It showed that the optimal operating point of ROC curve was 3.17，with high sensitivity(96.7%)，specificity(90.8%)，postive predictive value (93.3%)and negative predictive value(96.9%).Conclusions The real-time tissue elasticity imaging can provide a quantitative,noninvasive and convenient tool for evaluating the thyroid nodules.