CAJ | 학술논문

蕃杏科生物碱Mesembrine由Bodendorf研究小组于1957年从Mesembryanthemum tortuosum中分离得到.由于其结构特征和有趣的生物活性引起大量的关注.在过去的40年间,该化合物成为合成有机化学感兴趣的目标分子之一.到目前为止,文献中报道的全合成和形式合成路线已有40多种.对其中的31种全合成及形式合成路线进行了综述.
번행과생물감Mesembrine유Bodendorf연구소조우1957년종Mesembryanthemum tortuosum중분리득도.유우기결구특정화유취적생물활성인기대량적관주.재과거적40년간,해화합물성위합성유궤화학감흥취적목표분자지일.도목전위지,문헌중보도적전합성화형식합성로선이유40다충.대기중적31충전합성급형식합성로선진행료종술.
Mesembrine,an Aizoaceae alkaloia,was isolated from the Mesembryanthemum tortuosum and characterized by Bodendorf's group in 1957.In addition to its structural feature and interesting bioactivities has attracted much attention,mesembrine has been one of the most interesting targets in synthetic organic chemistry for the past 40 years.To date,over 40 total and formal syntheses have appeared.In this paper,31 total and formal syntheses of mesembrine are reviewed.