CAJ | 학술논문

背景:生物涂层假体在体内植入,受到复杂的化力学交互作用,临床返修病例随即增多.目的:总结化力学交互作用对热喷涂生物活性涂层的组织与性能影响方面的研究现状与进展.方法:应用计算机检索Elsevier数据库1999-01/2009-11的相关文章.检索词"apatite,coating,spraying",限定文章语言种类为English.同时计算机检索维普数据库1989-01/2009-11的相关文章,检索词"磷灰石,涂层,喷涂",限定文章语言种类为中文.纳入文章与热喷涂生物活性涂层的化力学作用密切相关的论文.排除重复性研究及与课题相关性较弱的文献.结果与结论:力学环境对生物活性涂层的溶解有显著作用,拉应力促进溶解而压应力抑制溶解.另外涂层溶解过程中涂层的力学性能同时受到影响,经过模拟体液浸泡后,涂层的力学性能下降.而植入体内后,由于骨组织参与及生物环境的影响,涂层性能有所升高.但目前仅有简单载荷对涂层组织与性能影响方面的研究,亟需进行拉、扭、疲劳等复合载荷与人体特殊化学环境的耦合场作用下,生物活性涂层的组织与性能的变化规律研究,以保障其结构完整性与性能完整性.
배경:생물도층가체재체내식입,수도복잡적화역학교호작용,림상반수병례수즉증다.목적:총결화역학교호작용대열분도생물활성도층적조직여성능영향방면적연구현상여진전.방법:응용계산궤검색Elsevier수거고1999-01/2009-11적상관문장.검색사"apatite,coating,spraying",한정문장어언충류위English.동시계산궤검색유보수거고1989-01/2009-11적상관문장,검색사"린회석,도층,분도",한정문장어언충류위중문.납입문장여열분도생물활성도층적화역학작용밀절상관적논문.배제중복성연구급여과제상관성교약적문헌.결과여결론:역학배경대생물활성도층적용해유현저작용,랍응력촉진용해이압응력억제용해.령외도층용해과정중도층적역학성능동시수도영향,경과모의체액침포후,도층적역학성능하강.이식입체내후,유우골조직삼여급생물배경적영향,도층성능유소승고.단목전부유간단재하대도층조직여성능영향방면적연구,극수진행랍、뉴、피로등복합재하여인체특수화학배경적우합장작용하,생물활성도층적조직여성능적변화규률연구,이보장기결구완정성여성능완정성.
BACKGROUND: With the bio-coated prosthesis implanted in the body by a complex interaction of chemo-mechanics, the cases of clinical revision increased.OBJECTIVE: To summarize the research progress of effect of interaction of chemo-mechanics on the microstructure and properties of thermal-sprayed bioactive coatings.METHODS: The relevant articles were retrieved from Elsevier with the key words of "apatite, coating, spraying" in English between January 1999 to November 2009. Meanwhile, the relevant articles were searched from database of Vip Information with the key words of "apatite, coating, spraying" in Chinese between January 1989 to November 2009. The articles that were highly related to the effect of chemo-mechanics on the microstructure and properties of thermal-sprayed bio-coatings were collected. The repetitive researching results and those with weak correlation were excluded.RESULTS AND CONCLUSION: It was shown that loading affected the dissolution of bio-coatings significantly. Tensile stress promoted the dissolution, while compressive stress inversely. In addition, the mechanical properties decreased after immersion in simulation body fluid. Moreover, the mechanical properties increased when it was implanted in bone tissue. However, there were only investigation of microstructure and properties of bio-coatings under simple loading. The coupling effect of complex loading, such as tension, torsion and fatigue, etc., and the specific chemical environment on the bio-coatings should be studied in order to ensure the integrity of its structure and properties.