CAJ | 학술논문

目的利用血氧水平依赖性功能性磁共振成像技术探讨健康成年人手部主动、被动对掌运动时的脑激活区的特点,为运动疗法治疗脑卒中提供理论依据.方法 9名健康成年人参加实验.以右手主动及被动对掌运动作为刺激模式,采用区块设计,利用SPM5软件进行数据处理.测量位于对侧感觉运动区及运动前区的脑激活区的中点,并统计各脑区出现激活的频数.结果主动及被动手对掌运动时主要激活的脑区包括:对侧感觉运动皮质(SMC)区、对侧运动前皮质(PMC)区、双侧辅助运动区(SMA)及同侧小脑,其中对侧SMC区的激活频率最高;被动运动时所激活的对侧SMC和PMC区的几何中心较主动运动时偏后.结论主动和被动对掌运动均可引起运动相关脑区激活,两种运动模式所激活脑区在分布上无明显差别,但被动运动所激活的对侧SMC和PMC区几何中心较主动运动偏后.
목적 이용혈양수평의뢰성공능성자공진성상기술탐토건강성년인수부주동、피동대장운동시적뇌격활구적특점,위운동요법치료뇌졸중제공이론의거.방법 9명건강성년인삼가실험.이우수주동급피동대장운동작위자격모식,채용구괴설계,이용SPM5연건진행수거처리.측량위우대측감각운동구급운동전구적뇌격활구적중점,병통계각뇌구출현격활적빈수.결과 주동급피동수대장운동시주요격활적뇌구포괄:대측감각운동피질(SMC)구、대측운동전피질(PMC)구、쌍측보조운동구(SMA)급동측소뇌,기중대측SMC구적격활빈솔최고;피동운동시소격활적대측SMC화PMC구적궤하중심교주동운동시편후.결론 주동화피동대장운동균가인기운동상관뇌구격활,량충운동모식소격활뇌구재분포상무명현차별,단피동운동소격활적대측SMC화PMC구궤하중심교주동운동편후.
Objective To assess differences in brain activation between active and passive movement of the right hand using blood oxygen level-dependent functional magnetic resonance imaging (BOLD-fMRI). Methods Nine healthy adult right handed volunteers were studied. fMRI was performed with active and passive finger-to-finger movement. Results Right hand active and passive movement produced significant activation in the contralateral sensorimotor cortex ( SMC ), the contralateral premotor cortex ( PMC ), bilaterally in the supplementary motor area (SMA) and in the ipsilateral cerebellum. The activated brain areas were centered on the contralateral SMC and PMC and located more forward during active movement than during passive movement. The contralateral SMC was the most strongly and the most frequently activated brain area. The contralateral posterior parietal cortex (PPC) was less relevant to the hand movements. Unlike active movement, passivemovement activated more areas in the posterior central gyrus than in the anterior central gyrus. Conclusions Both active and passive movement significantly activate the brain areas which are responsible for hand movement, but there are some differences in the locations of the cortex areas activated and in the incidence activation except in the contralateral SMC.