CAJ | 학술논문

目的探讨伽玛刀治疗原发性三叉神经痛的疗效及影响预后的因素.方法回顾性分析75例原发性三叉神经痛的患者行伽玛刀治疗的效果,均经OUR-XGD旋转式伽玛刀治疗,采用4～8 mm准直器,半月节照射采用多靶点,三叉神经根照射采用单靶点或双靶点,中心剂量70～90 Gy,脑干表面受量<15 Gy.通过随访患者疼痛发作的频率和程度的减轻评价疗效.结果随访时间为3～72个月,平均37.6个月,总有效率90.7%.4例患者2～3年后复发,6例在伽玛刀治疗后半年出现患侧面部麻木感,无其他并发症.经统计学分析,某些因素与疗效相关.结论伽玛刀治疗原发性三叉神经痛一种安全有效的方法,靶点选择、剂量选择、照射部位是影响预后的因素,而病史长短及疼痛分布与预后无相关性.
목적 탐토가마도치료원발성삼차신경통적료효급영향예후적인소.방법 회고성분석75례원발성삼차신경통적환자행가마도치료적효과,균경OUR-XGD선전식가마도치료,채용4～8 mm준직기,반월절조사채용다파점,삼차신경근조사채용단파점혹쌍파점,중심제량70～90 Gy,뇌간표면수량<15 Gy.통과수방환자동통발작적빈솔화정도적감경평개료효.결과 수방시간위3～72개월,평균37.6개월,총유효솔90.7%.4례환자2～3년후복발,6례재가마도치료후반년출현환측면부마목감,무기타병발증.경통계학분석,모사인소여료효상관.결론 가마도치료원발성삼차신경통일충안전유효적방법,파점선택、제량선택、조사부위시영향예후적인소,이병사장단급동통분포여예후무상관성.
Objective To investigate the effect and prognostic factors of gamma knife treatment for idi-opathic trigeminal neuralgia. Methods Retrospective analysis of 75 cases of patients with idiopathic trigeminal neuralgia were treated by gamma knife,32 cases of male,female 43 cases,have been considered by the OUR-XGD rotating gamma knife treatment,using 4 mm ～8 mm collimator,And a half section exposure multi-target, trigeminal nerve root exposure to a single target or two targets, the center dose of 70 ～ 90 Gy, the brain stem sur-face dose < 15 Gy. Through follow-up of patients with pain onset of the frequency and extent of reduction were e-valuated. Results Follow-up for 3 ～ 72 months, an average of 37.6 months, the total efficiency of 90. 7 %. 4 pa- tients relapse after 2 ～ 3 years, 6 cases had ipsilateral facial numbness after gamma knife treatment in six months, no other complications, the effect of gamma knife radiosurgery for primary trigeminal neuralgia has statis-tical significance with some factor. Conclusions Gamma knife radiosurgery for idiopathie trigeminal neuralgia is a safe and effective method,target selection ,dose selection and irradiated parts are obvious prognostie factors, The history of pain and distribution of the length are no eorrelation with prognosis.