CAJ | 학술논문

目的对长链脂肪乳注射液及中伥链脂肪乳注射液,分别配制成各种全合一(All-in-One)营养混合液,进行脂肪乳剂乳粒稳定性的对比研究.方法采用国产脂肪乳注射液、中伥链脂肪乳注射液,分别与氨基酸、葡萄糖、维生素、电解质和微量元素配制成(All-in-One).存放25℃1天,置4℃保存8天后25℃静置1天分别取样.同时用上市的长链脂肪乳注射液与中/长链脂肪乳注射液做平衡对照.用光散射分光光度计、库尔特微粒测定仪测定微粒的大小及其分布,较大粒子占理论总油量的质量百分比.并且测定样品的pH、渗透压等.结果在观察期内上市脂肪乳注射液和中伥链脂肪乳注射液其乳粒分布、乳粒大小、pH值和渗透压均无差别.
목적대장련지방유주사액급중창련지방유주사액,분별배제성각충전합일(All-in-One)영양혼합액,진행지방유제유립은정성적대비연구.방법채용국산지방유주사액、중창련지방유주사액,분별여안기산、포도당、유생소、전해질화미량원소배제성(All-in-One).존방25℃1천,치4℃보존8천후25℃정치1천분별취양.동시용상시적장련지방유주사액여중/장련지방유주사액주평형대조.용광산사분광광도계、고이특미립측정의측정미립적대소급기분포,교대입자점이론총유량적질량백분비.병차측정양품적pH、삼투압등.결과재관찰기내상시지방유주사액화중창련지방유주사액기유립분포、유립대소、pH치화삼투압균무차별.
To study the stability of fal emulsion in all types of AU-in-One nutrient admixtures prepared from on morket fat emnlsions and new MCT/LCTs. Admixtures were prepared from domestic fat emulstions and MCT/LCTs separately with amino acids,dextrose,vitamins, electrolyltes and trace elements. They were stored for one day at 25℃ followed by one day at 25℃ and eight days at 4℃. Admixtures of control group were prepared with fat emulsions and MCT/LCTs of other manufacturers and stored under the same conditions. Particle size and distribution, mass percentage of larger particles to theroretical total iol volume were measured by using light seattering spectrophotometer and coulter multisizer accucomp. Osmolality and pH of the samples were also measured. Stability of the all-in-one admixtures was monitored. The results showe that, compare with the control products, the particle size and distribution of domestic fat emulsions and MCT/LCTs, pH and osmolality of the admixtures remained stable during observation.