CAJ | 학술논문

目的:研究产自长白山地区的长白瑞香(Daphne koreana)的化学成分.方法:应用硅胶柱色谱,Sephadex LH-20和RP-18反相柱色谱的方法分离和纯化化合物,通过光谱方法及理化性质鉴定化合物结构.结果:从长白瑞香氯仿部位分离得到10个化合物,分别为:双白瑞香苷(1),7-甲氧基-木犀草素-5-O-β-D-葡萄糖苷(2),樱花苷(3),芜花苷(4),瑞香新素(5),异瑞香新素(6),5-去甲氧基瑞香新素(7),紫丁香苷(8),左旋松脂酚(9),左旋松脂酚-4-O-β-D-葡萄糖苷(10).结论:所有化合物均为首次从该植物中分得.
목적:연구산자장백산지구적장백서향(Daphne koreana)적화학성분.방법:응용규효주색보,Sephadex LH-20화RP-18반상주색보적방법분리화순화화합물,통과광보방법급이화성질감정화합물결구.결과:종장백서향록방부위분리득도10개화합물,분별위:쌍백서향감(1),7-갑양기-목서초소-5-O-β-D-포도당감(2),앵화감(3),무화감(4),서향신소(5),이서향신소(6),5-거갑양기서향신소(7),자정향감(8),좌선송지분(9),좌선송지분-4-O-β-D-포도당감(10).결론:소유화합물균위수차종해식물중분득.
AIM: To study the chemical constituents of the stems and barks of Daphne koreana from the hangbai Mountain in the North of China.METHODS: Compounds were separated by column chromatography with silica gel,Sephadex LH-20 and RP-18 silica gel.Their structures were elucidated on the basis of physiochemical and spectral analyses.RESULTS: Ten compounds were isolated from D.koreana and the structures were identified as daphnoretin-7-O-β-D-glucopyranoside (1), luteolin-7-methylether-5-O-β-D-glucopyranoside (2), sakuranin (3),yuankanin (4), daphneticin (5), isodaphneticin (6), 5'-demethoxydaphneticin (7), syringin (8), (-)-pinoresinol (9) and(-)-pinoresinol-4-O-β-D-glucopyranoside (10).CONCLUSION: Compounds 1～10 were isolated from this plant for the first time.[KEY WORDS] Daphne koreana; Thymelaeaceae; Chemical constituents[CLC Number] R284.1[Document code] A [Aiticle ID] 1672-3651(2008)06-0411-04[Foundation Item] This project was supported by the Science and Technology Commission Foundation of Shanghai (No.05DZ 19733)