CAJ | 학술논문

目的：对比评价3种可吸收性药膜对成人牙周炎的临床疗效。方法：应用刚果红染色记数、全自动生化酶分析等方法，检测螺旋霉素 ( SPI )、甲硝唑 ( MNZ )单方药膜及螺旋霉素-甲硝唑 ( SPI-MNZ )复方药膜局部用药前后各项临床指标、细菌学指标及生化指标的变化，对比评价其对成人牙周炎的治疗作用。结果： 3种药膜用药前后各项检测指标均有明显改变，其中SPI-MNZ复方药膜用药后各项指标的变化最为显著，与SPI 、MNZ 单方药膜相比具有显著性差异，而两种单方药膜相比无明显差异。结论：3种药膜局部应用均具有良好的临床疗效，而 SPI-MNZ 复方药膜比单方药膜能更有效地控制牙周组织炎症，改善牙周炎临床症状，具有更大的临床应用前景。
목적：대비평개3충가흡수성약막대성 인아주염적림상료효。방법：응용 강과홍염색기수、전자동생화매분석등방법，검측라선매소 ( SPI )、갑초서 ( MNZ )단방 약막급라선매소-갑초서 ( SPI-MNZ )복방약막국부용약전후각항림상지표、세균학지표급 생화지표적변화，대비평개기대성인아주염적치료작용。결과： 3충약막용약전후각항검 측지표균유명현개변，기중SPI-MNZ복방약막용약후각항지표적변화최위현저，여SPI 、MNZ 단방약막상비구유현저성차이，이량충단방약막상비무명현차이。결론：3충약막국부응용 균구유량호적림상료효，이 SPI-MNZ 복방약막비단방약막능경유효지공제아주조직염증， 개선아주염림상증상，구유경대적림상응용전경。
AIM: To compare and evaluate the effects of different periodontal drug membranes in the treatment of adult periodontitis. METHODS: The effects of spiramycin(SPI), metronidazole(MNZ) and SPI -MNZ mixed drug membranes in the treatment of adult periodontitis were assessed by the coloration of Congo-red and the analyse of biochemical enzymes. RESULTS: There were significant differences between the me dication groups and control groups. The SPI-MNZ mixed drug membranes were mo re effective than SPI or MNZ membranes. There were no statistical differen c es between SPI and MNZ drug membranes in regarding to the clin ical efficacy. CONCLUSIONS: Periodontal drug membranes are effective in the management of adult periodontitis.Compared with other simple membranes, SPI-MNZ mixed drug membranes ensure more satisfactory clinical ef fectiveness, predicting their greater potentiality of clinical application.