CAJ | 학술논문

目的比较宁红欣（国产红细胞生成素）和利血宝治疗肾性贫血的临床疗效。方法选择肾性贫血120例，随机分为宁红欣（2000U,皮下注射,每周3次）治疗组60例和利血宝（3000U,皮下注射,每周2次）对照组60例,均治疗12周。结果与治疗前比较，宁红欣总有效率86.7 %，显效率55.0 %。利血宝总有效率85.0 %，显效率50.0 %。两组间上述参数在治疗前、治疗后4、8、12周均无统计学差异（P>0.05）。结论宁红欣治疗肾性贫血与利血宝疗效基本相当。
목적비교저홍흔（국산홍세포생성소）화리혈보치료신성빈혈적림상료효。방법선택신성빈혈120례，수궤분위저홍흔（2000U,피하주사,매주3차）치료조60례화리혈보（3000U,피하주사,매주2차）대조조60례,균치료12주。결과여치료전비교，저홍흔총유효솔86.7 %，현효솔55.0 %。리혈보총유효솔85.0 %，현효솔50.0 %。량조간상술삼수재치료전、치료후4、8、12주균무통계학차이（P>0.05）。결론저홍흔치료신성빈혈여리혈보료효기본상당。
Objective　To compare the efficacy of Ninghongxin(a kind of domestic rhu-EPO) and Lixuebao in treatment of renal anemia.Methods　120 patients with renal anemia were randomly divided to receive Ninghongxin (n=60) in a dose of 2000U,three times every week for 12 weeks, and Lixuebao (n=60) in a dose of 3000U,twice every week for 12 weeks.Results　After treatment, the total effective rate of Ninghongxin was 86.7 %，the effective rate was 55 %.The total effective rate of Lixuebao was 85 %, the effective rate was 50 %.There is no significant difference between all parameters of the two groups.Conclusion　The study showed that the efficacy of Ninghongxin in the treatment of renal anemia is as effective as those of Lixuebao in doses stated above.