耳鼻咽喉-头颈外科
耳鼻嚥喉-頭頸外科
이비인후-두경외과
Chinese Archives of Otolaryngology Head and Neck Surgery
2001年
2期
105-106
,共2页
鼻咽癌%纤维蛋白%球蛋白类
鼻嚥癌%纖維蛋白%毬蛋白類
비인암%섬유단백%구단백류
目的：测定鼻咽癌患者血清β2-微球蛋白(β2-MG)和纤维连接蛋白(Fn)水平及意义。方法：采用放射免疫检测技术和琼脂扩散法检测60例鼻咽癌患者治疗前后血清β2-MG和Fn含量，并进行比较。结果：鼻咽癌患者血清β2-MG含量明显升高，但Fn含量却明显降低，均有显著性差异；治疗后鼻咽癌患者β2-MG含量明显下降，而Fn含量显著升高。结论：血清β2-MG和Fn含量的测定对鼻咽癌的诊断和预后评估有一定的意义。
目的：測定鼻嚥癌患者血清β2-微毬蛋白(β2-MG)和纖維連接蛋白(Fn)水平及意義。方法：採用放射免疫檢測技術和瓊脂擴散法檢測60例鼻嚥癌患者治療前後血清β2-MG和Fn含量，併進行比較。結果：鼻嚥癌患者血清β2-MG含量明顯升高，但Fn含量卻明顯降低，均有顯著性差異；治療後鼻嚥癌患者β2-MG含量明顯下降，而Fn含量顯著升高。結論：血清β2-MG和Fn含量的測定對鼻嚥癌的診斷和預後評估有一定的意義。
목적：측정비인암환자혈청β2-미구단백(β2-MG)화섬유련접단백(Fn)수평급의의。방법：채용방사면역검측기술화경지확산법검측60례비인암환자치료전후혈청β2-MG화Fn함량，병진행비교。결과：비인암환자혈청β2-MG함량명현승고，단Fn함량각명현강저，균유현저성차이；치료후비인암환자β2-MG함량명현하강，이Fn함량현저승고。결론：혈청β2-MG화Fn함량적측정대비인암적진단화예후평고유일정적의의。
Objective:To study the clinical significance of β2-microglobin(β2-MG)and fibronection (Fn) contents in patients with nasopharyngeal carcinoma.Methods:The contents of serum β2-MG and Fn were detected by radioimmunoassay and agar-diffusion methods in 60 patients with nasopharyngeal carcinoma before and after radiotherapy,also in 60 normal subjects as control group.Results:The contents of serum β2-MG and Fn were 2.99±1.11mg/L(β2-MG)and 134.60±28.93mg/L(Fn) in 60 patients with nasopharyngeal carcinoma,2.16±0.50mg/L(β2-MG)and 196.16±34.65mg/L(Fn)in 60 health subjects,respectively.Those results showed that the content of β2-MG in patients group was higher than that in control group (P＜0.05),and the content of Fn in patients group was lower than that in control group(P＜0.05).After radiotherapy of patients group,the content of β2-MG were lower(2.16±0.55mg/L)than that before radiotherapy(P＜0.05).Conversely,the content of Fn was higher(180.53±34.66mg/L)than after radiotherapy(P＜0.05).Conclusions:The detection of serum β2-MG and Fn have clinical significance on the evaluation prognosis of patients with nasopharyngeal carcinoma.
