CAJ | 학술논문

目的探讨脑瘫儿童脑室周围白质软化症(PVL)的MRI表现特点。方法回顾性分析83例缺氧缺血性脑病导致PVL的脑瘫患儿（其中早产23例）的临床资料和MRI表现。结果 ①PVL导致脑瘫儿童的MRI表现：脑白质减少主要发生在侧脑室三角区﹑体部周围及半卵圆中心;脑白质信号异常主要发生在侧脑室三角区、体部周围和半卵圆中心;脑室扩大变形；脑沟裂池扩大增宽;胼胝体异常。其他MRI的异常表现为脑皮层萎缩软化和基底节变性。②早产儿和足月儿PVL的不同MRI特点：早产儿和足月儿在脑白质区出现长T1、明显长T2信号的软化、囊变灶和脑室变形（脑室边缘凹凸不平）等均有显著性差异。结论 MRI可清晰显示脑瘫患儿PVL的MRI特点、病变程度、范围以及早产儿与足月儿PVL的不同之处。早产儿发生PVL的程度较足月儿重，易出现侧脑室旁脑白质的长T1、明显长T2信号的软化、囊变灶及侧脑室不规则扩大、变形。
목적 탐토뇌탄인동뇌실주위백질연화증(PVL)적MRI표현특점。방법 회고성분석83례결양결혈성뇌병도치PVL적뇌탄환인（기중조산23례）적림상자료화MRI표현。결과 ①PVL도치뇌탄인동적MRI표현：뇌백질감소주요발생재측뇌실삼각구﹑체부주위급반란원중심;뇌백질신호이상주요발생재측뇌실삼각구、체부주위화반란원중심;뇌실확대변형；뇌구렬지확대증관;변지체이상。기타MRI적이상표현위뇌피층위축연화화기저절변성。②조산인화족월인PVL적불동MRI특점：조산인화족월인재뇌백질구출현장T1、명현장T2신호적연화、낭변조화뇌실변형（뇌실변연요철불평）등균유현저성차이。결론 MRI가청석현시뇌탄환인PVL적MRI특점、병변정도、범위이급조산인여족월인PVL적불동지처。조산인발생PVL적정도교족월인중，역출현측뇌실방뇌백질적장T1、명현장T2신호적연화、낭변조급측뇌실불규칙확대、변형。
Objective To study the MRI features of children with cerebralpalsy(CP) resulting from anoxia.Methods The clinical and MRI findings in 83 premature or mature children affected by cerebral palsy resulting from PVL were reviewed retrospectively to search for the MRI features and the data were analyzed by statistic. Results 1. MRI features of CP children resulting from anoxia were clearly demonstrated：1) MRI features of PVL: reduction of white matter ；T2W signal hyperintensity in white matter； ventricle enlarged or irregular appearance; lateral fissure；deepened or widened Sulci;and abnormal corpus callossum; 2) other abnormal MRI features: basal ganglion damaged; cerebral cortex atrophy or malacia. 2.Differences in MRI features between premature and mature CP children: there are significant differences between premature and mature children at malacia and cyst of deep white matter; enlargement and irregularity of the lateral ventricles. Conclusions MRI examination can clearly display the level and scope of focus of PVL,and the differences in MRI features between premature and mature children.The level and degree of premature children are deeper and more extensive than those of mature children.Cyst and malacia in deep white matter,enlargement and irregularity of the lateral ventricles occur more frequantly in premature children.