CAJ | 학술논문

目的探讨输卵管切除后对卵巢功能的影响。方法选择因异位妊娠行一侧输卵管切除的患者手术侧卵巢与对侧卵巢及行输卵管切除的患者与双侧输卵管健全的患者，在行体外受精-胚胎移植(IVF-ET)中其卵巢对控制性超促排卵的反应。结果输卵管切除侧卵巢尽管其体积无明显改变，但其卵泡数及所获卵子数明显少于健侧卵巢。而存留一侧输卵管患者与对照组相比，在卵巢大小、用药量、用药天数、子宫内膜厚度、卵泡数及所获卵子数上并无显著差别。结论输卵管切除术在短期内虽然不能影响卵巢的体积，但却降低了同侧卵巢的储备功能。因此，临床上对有生育要求的异位妊娠患者，应尽可能地保留患侧输卵管。对于输卵管积水行体外受精-胚胎移植者，如对侧卵巢缺如或卵巢功能低下，不宜做预防性输卵管切除术。
목적탐토수란관절제후대란소공능적영향。방법선택인이위임신행일측수란관절제적환자수술 측란소여대측란소급행수란관절제적환자여쌍측수란관건전적환자，재행체외수정-배태이식(IVF-ET)중기 란소대공제성초촉배란적반응。결과수란관절제측란소진관기체적무명현개변，단기란포수급소획란자수명 현소우건측란소。이존류일측수란관환자여대조조상비，재란소대소、용약량、용약천수、자궁내막후도、란포수 급소획란자수상병무현저차별。결론수란관절제술재단기내수연불능영향란소적체적，단각강저료동측란소 적저비공능。인차，림상상대유생육요구적이위임신환자，응진가능지보류환측수란관。대우수란관적수행체외 수정-배태이식자，여대측란소결여혹란소공능저하，불의주예방성수란관절제술。
Objective To investigate the effect of salpingectomy on the function of ovary in patients undergoing an IVF - ET treatment cycle. Methods The ovarian response to superovulation were evaluated in patients who previously had undergone unilateral salpingectomy because of ectopic pregnancy(study group)and patients with unexplained infertil ity with intact salpinx served as controls. Results There were no differences in the total numbers of follicles,oocytes re trived from both ovaries and the cycle characteristics between study and control groups. Among the patients who had un dergone salpingectomy, significantly fewer follicles developed and consequently fewer oocytes were retrieved from the o vary on the operated side( P ＜ 0.01, P ＜ 0.05 ). Conclusion Salpingectomy has no effect on ovarian volume in short pe riod, but has detrimental effect on ipsilateral ovarian function. So the salpingectomy can not be performed in patients un dergoing IVF - ET in whom the other ovary has already been damaged or missing. We should try our best to reserve the salpinx during tubal pregnancy if the patients need to keep their reproductive capabilities.