现代预防医学
現代預防醫學
현대예방의학
MODERN PREVENTIVE MEDICINE
2001年
1期
1-3
,共3页
庚型肝炎%献血员%传播途径%危险因素
庚型肝炎%獻血員%傳播途徑%危險因素
경형간염%헌혈원%전파도경%위험인소
目的:了解献血员中HGV感染状况,探讨感染的危险因素以及是否存在输血之外的传播途径。方法:采用ELISA法和RT—PCR法,对泰安市189名无偿献血员、404名职业献血员、169名单采血浆献血员进行抗-HGV和HGVRNA检测;并对部分抗-HGV阳性献血员及其家属进行流行病学调查。结果:三种献血员人群抗-HGV阳性率分别为1.59%(3/189)、0.99%(4/404)和5.33%(9/169);HGVRNA阳性率分别为0%、0.25%(1/404)和2.37%(4/169)。流行病学调查显示可能存在经母婴传播和性行为传播的感染者。结论:单采血浆和不洁注射为感染危险因素;HGV有可能经母婴垂直和性行为传播。
目的:瞭解獻血員中HGV感染狀況,探討感染的危險因素以及是否存在輸血之外的傳播途徑。方法:採用ELISA法和RT—PCR法,對泰安市189名無償獻血員、404名職業獻血員、169名單採血漿獻血員進行抗-HGV和HGVRNA檢測;併對部分抗-HGV暘性獻血員及其傢屬進行流行病學調查。結果:三種獻血員人群抗-HGV暘性率分彆為1.59%(3/189)、0.99%(4/404)和5.33%(9/169);HGVRNA暘性率分彆為0%、0.25%(1/404)和2.37%(4/169)。流行病學調查顯示可能存在經母嬰傳播和性行為傳播的感染者。結論:單採血漿和不潔註射為感染危險因素;HGV有可能經母嬰垂直和性行為傳播。
목적:료해헌혈원중HGV감염상황,탐토감염적위험인소이급시부존재수혈지외적전파도경。방법:채용ELISA법화RT—PCR법,대태안시189명무상헌혈원、404명직업헌혈원、169명단채혈장헌혈원진행항-HGV화HGVRNA검측;병대부분항-HGV양성헌혈원급기가속진행류행병학조사。결과:삼충헌혈원인군항-HGV양성솔분별위1.59%(3/189)、0.99%(4/404)화5.33%(9/169);HGVRNA양성솔분별위0%、0.25%(1/404)화2.37%(4/169)。류행병학조사현시가능존재경모영전파화성행위전파적감염자。결론:단채혈장화불길주사위감염위험인소;HGV유가능경모영수직화성행위전파。
Objective: To understand the state of HGV infection, the route of transmission except blood transfusion and the risk factors in blood donors. Methods: Anti-HGV and HGVRNA were tested by ELISA and reverse transcription polgmerase chain reaction for 189 volunteer blood donors, 404 professional blood donors and 169 plasmapheresis blood donors in Taian City. Epidemiological survey was carried out in part of anti-HGV positive blood donors and their relatives. Rusults: The positive rates of antibodies detected were 1.59% (3/189)、 0. 99 (4/404) and 5.33% (9/169) respectively; the positive rates of HGVRNA were 0% 、0. 25% (1/404) and 2.37% (4/169) respectively. Mother to infant transmission in two persons infected and transmission of sexual behaviour in one person have been discovered. Conclusion: Poor sterilization in plasmapheresis and not clean injection history are risk factors of the infection; HGV infection may be transmitted by mother-infant and sexual behaviour routes.