上海大学学报(英文版)
上海大學學報(英文版)
상해대학학보(영문판)
JOURNAL OF SHANGHAI UNIVERSITY (ENGLISH EDITION)
1999年
1期
81-83
,共3页
卢大用%沈文达%曹静懿%卢廷仁%崔保义%富智愚
盧大用%瀋文達%曹靜懿%盧廷仁%崔保義%富智愚
로대용%침문체%조정의%로정인%최보의%부지우
antineoplastic drugs%magnetic biology%magnetized water%cancer chemotherapy%detoxication
To broaden the applications of magnetized water(MW) in medical science, the possible detoxicative effect of MW to anticancer drugs in vivo were studied. After being given ip with cyclophosphomide (CTX) 500 mg/kg, cisplatin (DDP) 40 mg/kg, harringtonine (HA) 20 mg/kg, mitomycin C (MMC) 8 mg/kg, lycobetaine (Lyc) 200 mg/kg, respectively, the mice were given MW ip 0.2 ml for 7 days. The average life span was calculated for each group. After being given subacutely lower doses of anticancer drugs ( CTX 100 mg/kg, HA 3 mg/kg ) ip 3 times, the mice were given MW ip 0.2 ml for 7 days and the blood white cells were counted as routine. It was shown that the mice in MW groups after ip anticancer drugs survived longer than those without MW. The effects of various anticancer drugs on life span were different. The white cell numbers of groups with MW were higher than that of the groups without MW. So it is possible that MW can remarkably extend the life span of mice and attenuate the leukopenia by mitigating the toxicity of anticancer drugs in vivo.