实用放射学杂志
實用放射學雜誌
실용방사학잡지
JOURNAL OF PRACTICAL RADIOLOGY
2010年
2期
175-178
,共4页
王华斌%李苏建%王中秋%卢光明
王華斌%李囌建%王中鞦%盧光明
왕화빈%리소건%왕중추%로광명
肺%孤立性肺结节%正电子发射断层显像术%计算机体层摄影%双源
肺%孤立性肺結節%正電子髮射斷層顯像術%計算機體層攝影%雙源
폐%고립성폐결절%정전자발사단층현상술%계산궤체층섭영%쌍원
lung solitary pulmonary nodule%positron emission tomography%CT,dual source
目的 探讨18-氟-脱氧葡萄糖(~(18)F-FDG)PET/CT显像及Siemens双源CT的LungCare软件对孤立性肺结节(SPN)的辅助诊断能力及适用范围.方法 回顾分析经病理证实的24例SPN患者的PET-CT图像资料,并与利用双源CT的LungCare软件分析SPN进行比较研究.用χ~2检验对2种检查方法的评价结果进行统计学分析,以P<0.05作为差异有显著意义.结果 在24例SPN中,恶性结节15例,良性结节9例.LungCare软件评估其良恶性的准确性、敏感性、特异性、阳性预测值、阴性预测值分别为83.3%、80.0%、88.8%、92.3%、72.7%,PET-CT评估其良恶性的准确性、敏感性、特异性、阳性预测值、阴性预测值分别为87.5%、93.3%、77.7%,87.5%、87.5%.LungCare软件和PET/CT定性SPN的准确性相当,两者之间并不存在明显的差异(P>0.05).PET/CT的敏感性、阴性预测值明显高于LungCare软件,但其特异性、阳性预测值明显低于LungCare软件(P<0.05).结论 ~(18)F-FDG PET-CT对肺结节的诊断有一定辅助作用,适用于对孤立性肺结节的良恶性鉴别诊断.PET/CT密切结合LungCare软件,可进一步提高诊断正确率.
目的 探討18-氟-脫氧葡萄糖(~(18)F-FDG)PET/CT顯像及Siemens雙源CT的LungCare軟件對孤立性肺結節(SPN)的輔助診斷能力及適用範圍.方法 迴顧分析經病理證實的24例SPN患者的PET-CT圖像資料,併與利用雙源CT的LungCare軟件分析SPN進行比較研究.用χ~2檢驗對2種檢查方法的評價結果進行統計學分析,以P<0.05作為差異有顯著意義.結果 在24例SPN中,噁性結節15例,良性結節9例.LungCare軟件評估其良噁性的準確性、敏感性、特異性、暘性預測值、陰性預測值分彆為83.3%、80.0%、88.8%、92.3%、72.7%,PET-CT評估其良噁性的準確性、敏感性、特異性、暘性預測值、陰性預測值分彆為87.5%、93.3%、77.7%,87.5%、87.5%.LungCare軟件和PET/CT定性SPN的準確性相噹,兩者之間併不存在明顯的差異(P>0.05).PET/CT的敏感性、陰性預測值明顯高于LungCare軟件,但其特異性、暘性預測值明顯低于LungCare軟件(P<0.05).結論 ~(18)F-FDG PET-CT對肺結節的診斷有一定輔助作用,適用于對孤立性肺結節的良噁性鑒彆診斷.PET/CT密切結閤LungCare軟件,可進一步提高診斷正確率.
목적 탐토18-불-탈양포도당(~(18)F-FDG)PET/CT현상급Siemens쌍원CT적LungCare연건대고립성폐결절(SPN)적보조진단능력급괄용범위.방법 회고분석경병리증실적24례SPN환자적PET-CT도상자료,병여이용쌍원CT적LungCare연건분석SPN진행비교연구.용χ~2검험대2충검사방법적평개결과진행통계학분석,이P<0.05작위차이유현저의의.결과 재24례SPN중,악성결절15례,량성결절9례.LungCare연건평고기량악성적준학성、민감성、특이성、양성예측치、음성예측치분별위83.3%、80.0%、88.8%、92.3%、72.7%,PET-CT평고기량악성적준학성、민감성、특이성、양성예측치、음성예측치분별위87.5%、93.3%、77.7%,87.5%、87.5%.LungCare연건화PET/CT정성SPN적준학성상당,량자지간병불존재명현적차이(P>0.05).PET/CT적민감성、음성예측치명현고우LungCare연건,단기특이성、양성예측치명현저우LungCare연건(P<0.05).결론 ~(18)F-FDG PET-CT대폐결절적진단유일정보조작용,괄용우대고립성폐결절적량악성감별진단.PET/CT밀절결합LungCare연건,가진일보제고진단정학솔.
Objective To evaluate the auxiliary diagnostic ability and applicability of ~(18)F-FDG PET/CT and the LungCare soft-ware of dual source CT in solitary pulmonary nodule(SPN). Methods 28 patients with SPN proved by pathologically were examined by ~(18)F-FDG PET/CT and LungCare software of dual source CT. ~(18)F-FDG PET/CT and LungCare software of dual source CT data were analysed comparatively in terms of the diagnostic accuracy in distinguishing malignant and benign. All data were analyzed for significance by using the χ~2-test,the value of P<0.05 was accepted as significance. Results There were 15 malignant and 9 benign nodules. In evaluating SPN,the diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 80.0% ,88.8% ,83.3%,92.3% and 72.7% with ~(18)F-FDG PET/aT respectively,and 93.3% ,77.7% ,87.5%,87.5% and 87.5% with LungCare software, respectively. To evaluate SPN,LungCare software and ~(18)F-FDO PET/CT was not significant difference in accuracy(P>0.05) ,while there were significant differences in sensitivity , specificity , positive and negative predictive value (P< 0.05). The sensitivity and negative predictive values with~(18)F-FDG PET/aT were much better than that with LungCare software, but the specificity and positive predictive values were less than that with LungCare software. Conclusion ~(18)F-FDG PET/CT has certain auxiliary function in distinguishing benign SPN from malignant SPN,it combining with LungCare software , the accuracy of diagnosis can be improved.
