CAJ | 학술논문

目的探讨125Ⅰ粒子植入治疗脊椎转移瘤的初步疗效.方法　对15例转移瘤患者的22处病灶于术前制订125Ⅰ粒子植入计划,确定粒子数量和分布.在CT引导下植入125Ⅰ粒子,治疗后3~6个月观察疼痛缓解情况和瘤灶大小变化.结果22处脊椎和椎旁转移瘤植入粒子后,疼痛完全缓解(0级)14处,部分缓解(Ⅰ级)6处,轻微缓解(Ⅱ级)2处,总有效率为90.9%(u=5.41,P<0.001);脊椎和椎旁转移瘤的瘤灶大小变化:4处完全缓解,12处部分缓解,6处病变稳定,局部控制率为72.7%.结论 CT引导下125Ⅰ粒子植入治疗脊椎转移瘤是一种安全、微创、疗效好的方法.
목적 탐토125Ⅰ입자식입치료척추전이류적초보료효.방법　대15례전이류환자적22처병조우술전제정125Ⅰ입자식입계화,학정입자수량화분포.재CT인도하식입125Ⅰ입자,치료후3~6개월관찰동통완해정황화류조대소변화.결과22처척추화추방전이류식입입자후,동통완전완해(0급)14처,부분완해(Ⅰ급)6처,경미완해(Ⅱ급)2처,총유효솔위90.9%(u=5.41,P<0.001);척추화추방전이류적류조대소변화:4처완전완해,12처부분완해,6처병변은정,국부공제솔위72.7%.결론 CT인도하125Ⅰ입자식입치료척추전이류시일충안전、미창、료효호적방법.
Objective To evaluate the clinical value of 125Ⅰ seeds implantation for vertebra metastasis.Methods By CT guide, 125Ⅰ seeds were implanted in 22 vertebra metastasis of 15 patients.3-6 months later,pain and metastasis biggest diameter were observed to judge therapeutic effect.Results In 22 spinal and paraspinal metastases after implantation of particles,complete remission of pain(O grade)14,partial remission (I grade)6,a slight relief(Ⅱ grade)2,the total effective rate was 90.9%(u=5.41,P<0.001).Change of spinal and paraspinal metastases size:4 complete remission,12 partial response,6 stable disease,local control rate Was 72.7%.Conclusion CT guided 125Ⅰseed implantation in vertebra metastasis is safe,minimally invasive,and possesses a high efficacy.