CAJ | 학술논문

慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者在自然病程中普遍存在营养不良和不同程度的骨骼肌萎缩,低体质量及骨骼肌消耗不仅直接导致COPD患者外周骨骼肌功能障碍、呼吸肌无力、运动耐力和生活质量降低,也严重影响其预后和病死率.通过对COPD患者骨骼肌萎缩发病机制的不断了解,才能对COPD患者营养不良、骨骼肌萎缩进行有效的干预,改善甚至预防这种病理状态的发生,从而提高COPD患者的生活质量,降低COPD患者的病死率.
만성조새성폐질병(chronic obstructive pulmonary disease,COPD)환자재자연병정중보편존재영양불량화불동정도적골격기위축,저체질량급골격기소모불부직접도치COPD환자외주골격기공능장애、호흡기무력、운동내력화생활질량강저,야엄중영향기예후화병사솔.통과대COPD환자골격기위축발병궤제적불단료해,재능대COPD환자영양불량、골격기위축진행유효적간예,개선심지예방저충병리상태적발생,종이제고COPD환자적생활질량,강저COPD환자적병사솔.
The patients with chronic obstructive pulmonary disease (COPD) generally have malnutrition and different level's skeletal muscle atrophy, low body mass and skeletal muscle wasting not only induce peripheral skeletal muscle dysfunction, respiratory muscle's acratia, exercise in tolerance and reduction of life quality in patients with COPD, but also heavily influence its prognosis and case fatality rate. Through uninterrupted comprehend pathogenesy of skeletal muscle atrophy in COPD, we can do some effective intervention to malnutrition and skeletal muscle atrophy in patients with COPD, and we can improve,even prevent this pathologic state, consequently improre life quanlity and decrease death rate of patients with COPD.