中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
23期
24-26
,共3页
江秀丽%陈燕%庄茂友%张红
江秀麗%陳燕%莊茂友%張紅
강수려%진연%장무우%장홍
诱发电位%躯体感觉%颈椎病%早期诊断
誘髮電位%軀體感覺%頸椎病%早期診斷
유발전위%구체감각%경추병%조기진단
Evoked potentials,somatosensory%Cervical spondylosis%Early diagnosis
目的 探讨躯体感觉诱发电位(SEP)对神经根型颈椎病(CSR)的早期诊断价值.方法 对65例病程3个月内的CSR患者(病例组)进行正中神经SEP(SEPm)的检测,并选取30例健康志愿者作为对照组.所有患者均行颈椎MRI检查,比较SEPm与MRI的检查结果,病程12个月时复查SEPm及MRI.结果 病例组SEPm检测N11、N13峰潜伏期及N9～N13峰间期在病程3个月内分别为(12.92±0.97)、(14.81±1.16)、(4.45±0.65)ms,在病程12个月时分别为(14.20±1.06)、(16.35±1.75)、(5.62±0.88)ms,均较对照组的(11.65±0.69)、(13.26±0.78)、(3.56±0.31)ms明显延长(P＜0.05),且病程12个月时较病程3个月内延长(P＜0.05).病例组在病程3个月内的SEPm阳性率为87.69%(57/65),明显高于MRI的70.77%(46/65),两者阳性率比较差异有统计学意义(x2=4.35,P＜0.05);在病程12个月时SEPm、MRI阳性率分别为90.77%(59/65)、81.54%(53/65),两者阳性率比较差异无统计学意义(x2=1.56,P＞0.05).结论 SEP对CSR的早期诊断有重要价值,可作为常规检查手段.
目的 探討軀體感覺誘髮電位(SEP)對神經根型頸椎病(CSR)的早期診斷價值.方法 對65例病程3箇月內的CSR患者(病例組)進行正中神經SEP(SEPm)的檢測,併選取30例健康誌願者作為對照組.所有患者均行頸椎MRI檢查,比較SEPm與MRI的檢查結果,病程12箇月時複查SEPm及MRI.結果 病例組SEPm檢測N11、N13峰潛伏期及N9～N13峰間期在病程3箇月內分彆為(12.92±0.97)、(14.81±1.16)、(4.45±0.65)ms,在病程12箇月時分彆為(14.20±1.06)、(16.35±1.75)、(5.62±0.88)ms,均較對照組的(11.65±0.69)、(13.26±0.78)、(3.56±0.31)ms明顯延長(P＜0.05),且病程12箇月時較病程3箇月內延長(P＜0.05).病例組在病程3箇月內的SEPm暘性率為87.69%(57/65),明顯高于MRI的70.77%(46/65),兩者暘性率比較差異有統計學意義(x2=4.35,P＜0.05);在病程12箇月時SEPm、MRI暘性率分彆為90.77%(59/65)、81.54%(53/65),兩者暘性率比較差異無統計學意義(x2=1.56,P＞0.05).結論 SEP對CSR的早期診斷有重要價值,可作為常規檢查手段.
목적 탐토구체감각유발전위(SEP)대신경근형경추병(CSR)적조기진단개치.방법 대65례병정3개월내적CSR환자(병례조)진행정중신경SEP(SEPm)적검측,병선취30례건강지원자작위대조조.소유환자균행경추MRI검사,비교SEPm여MRI적검사결과,병정12개월시복사SEPm급MRI.결과 병례조SEPm검측N11、N13봉잠복기급N9～N13봉간기재병정3개월내분별위(12.92±0.97)、(14.81±1.16)、(4.45±0.65)ms,재병정12개월시분별위(14.20±1.06)、(16.35±1.75)、(5.62±0.88)ms,균교대조조적(11.65±0.69)、(13.26±0.78)、(3.56±0.31)ms명현연장(P＜0.05),차병정12개월시교병정3개월내연장(P＜0.05).병례조재병정3개월내적SEPm양성솔위87.69%(57/65),명현고우MRI적70.77%(46/65),량자양성솔비교차이유통계학의의(x2=4.35,P＜0.05);재병정12개월시SEPm、MRI양성솔분별위90.77%(59/65)、81.54%(53/65),량자양성솔비교차이무통계학의의(x2=1.56,P＞0.05).결론 SEP대CSR적조기진단유중요개치,가작위상규검사수단.
Objective To investigate the value ofsomatosensory evoked potentials (SEP) in early diagnosis of cervical spondylotic radiculopathy (CSR). Methods The median nerve SEP (SEPm) was examined in 65 cases of CSR (experimental group), and was compared with 30 controls(control group). All the patients were examined by MRI of the cervical spine which were compared with SEPm. All cases were followed up 12 months, at the same time MRI and SEPm were examined repeatedly. Results The experimental group with CSR had significantly prolonged peak latency (PL) of N11 and N13 wave and interpeak latency(IPL) of wave N9-NI3 within 3 months [( 12.92 ± 0.97), (14.81 ± 1.16), (4.45 ±0.65)ms] and at the 12th month [( 14.20 ± 1.06), ( 16.35 ± 1.75), (5.62 ± 0.88) ms] compared with those of control group[(11.65 ± 0.69), (13.26 ± 0.78), (3.56 ± 0.31 ) ms](P＜ 0.05). The PL of Nll and N13 wave and IPL of wave N9-N13 significantly prolonged at the 12th month compared with those within 3 months.SEPm provided more sensitive modality for the diagnosis[87.69%(57/65 )] of CSR within 3 months than that of MRI [70.77% (46/65)] ( X2 =4.35,P ＜0.05). While there was no significant difference in sensitive between SEPm [90.77%(59/65)] and MRI [81.54%(53/65)] at the 12th month (X2= 1.56,P＞0.05).Conclusion SEP is valuable for the early diagnosis of CSR and may be clinically utilized as a sensitive indicator of CSR.
