CAJ | 학술논문

目的了解≥40岁广东省直机关公务员糖尿病视网膜病变(DR)患病率及其危险因素.方法以来我院体检中心体检≥40岁广东省直机关公务员为调查对象,共3844人,进行糖尿病(DM)筛查.根据WHO 1999年DM的诊断标准确诊并进一步行DR筛查.具体包括问卷调查、一般项目检查、实验室检测、一般眼科检查、眼底照相和光相干断层扫描检查等.分析DM患者中DR的患病率及危险因素.结果共确诊DM患者155例,DM患病率为4.03％.155例DM患者中发现DR 11例,占7.10％.DR患者和非DR患者间空腹血糖、总胆固醇、低密度脂蛋白及是否使用胰岛素比较,差异具有统计学意义(t=3.158,2.200,2.050;x2 =5.128;P＜0.05).高的空腹血糖(Wald值=7.62,标准误=0.12,相对危险度估计值=1.40,相对危险度95％可信区间:1.10～1.77,P=0.01)和使用胰岛素(Wald值=4.34,标准误=0.94,相对危险度估计值=7.01,相对危险度95％可信区间:1.12～43.76,P=0.04)是DR发生的独立危险因素.结论 ≥40岁广东省直机关公务员DM患者中DR患病率为7.10％.高的空腹血糖水平和使用胰岛素是DR发生的独立危险因素.
목적 료해≥40세광동성직궤관공무원당뇨병시망막병변(DR)환병솔급기위험인소.방법 이래아원체검중심체검≥40세광동성직궤관공무원위조사대상,공3844인,진행당뇨병(DM)사사.근거WHO 1999년DM적진단표준학진병진일보행DR사사.구체포괄문권조사、일반항목검사、실험실검측、일반안과검사、안저조상화광상간단층소묘검사등.분석DM환자중DR적환병솔급위험인소.결과 공학진DM환자155례,DM환병솔위4.03％.155례DM환자중발현DR 11례,점7.10％.DR환자화비DR환자간공복혈당、총담고순、저밀도지단백급시부사용이도소비교,차이구유통계학의의(t=3.158,2.200,2.050;x2 =5.128;P＜0.05).고적공복혈당(Wald치=7.62,표준오=0.12,상대위험도고계치=1.40,상대위험도95％가신구간:1.10～1.77,P=0.01)화사용이도소(Wald치=4.34,표준오=0.94,상대위험도고계치=7.01,상대위험도95％가신구간:1.12～43.76,P=0.04)시DR발생적독립위험인소.결론 ≥40세광동성직궤관공무원DM환자중DR환병솔위7.10％.고적공복혈당수평화사용이도소시DR발생적독립위험인소.
Objective To learn the prevalence and risk factors of diabetic retinopathy (DR) of provincial civil servants (more than 40 years old) in Guangdong,China.Methods Total of 3844 Guangdong provincial civil servants over 40 years old were enrolled in this study.All participants diagnosed with diabetes underwent a complete ophthalmologic examination,including stereoscopic fundus photography and optical coherence tomography.Photographs were graded in a masked manner to assess the presence and severity of DR and diabetic macular edema (DME).Results Of 3844 civil servants,DM was confirmed in 155 patients,the prevalence was 4.03％.Of 155 DM patients,DR was in 11 patients,the DR prevalence was 7.10％.There were statistically differences on the fasting blood glucose (FBG),total cholesterol,low density lipoprotein and whether or not to use insulin between DR group and non DR group (t=3.158,2.200,2.050; x2 =5.128; P ＜ 0.05). High-FBG values,high hlood lipids,INS applications had accelerated the occurrence and development of DR.The high FBG and the insulin using were the independent risk factors of DR.Conclusions DR prevalence is 7.10％ in Guangdong provincial civil servants more than 40 years old.The high FBG and the insulin using are the independent risk factors of DR.