CAJ | 학술논문

目的探讨腹腔镜肝切除术(laparoscopic hepatectomy,LH)与开腹肝切除术(open hepatectomy,OH)治疗肝癌的临床疗效.方法广州医学院第二附属医院2008年1月至2010年12月期间收治原发性肝细胞癌患者45例,将其分为2组,LH组21例,OH组24例.比较2组患者术中、术后的情况与生存率,评价其疗效.结果本组患者术中失血量和输血量LH组显著高于OH组(分别x2=3.973,x2=4.862,均P＜0.05),近期并发症发生率LH组(2例)显著低于OH组(9例)(x2=4.746,P＜0.05)；总住院天数LH组为(17.3±5.0)d,OH组为(21.5±5.1)d,2组比较差异有统计学意义(t=-2.717,P＜0.05).2组患者随访的总生存率比较差异无统计学意义(x2=0.172,P ＞0.05).LH组的无瘤生存率为52.4％,显著高于OH组(25.1％,x2=4.543,P＜0.05).结论腹腔镜与开腹肝切除均为肝癌治疗的有效方法,腹腔镜术式近期并发症少,住院时间短,但两组总体生存率无差异.
목적 탐토복강경간절제술(laparoscopic hepatectomy,LH)여개복간절제술(open hepatectomy,OH)치료간암적림상료효.방법 엄주의학원제이부속의원2008년1월지2010년12월기간수치원발성간세포암환자45례,장기분위2조,LH조21례,OH조24례.비교2조환자술중、술후적정황여생존솔,평개기료효.결과 본조환자술중실혈량화수혈량LH조현저고우OH조(분별x2=3.973,x2=4.862,균P＜0.05),근기병발증발생솔LH조(2례)현저저우OH조(9례)(x2=4.746,P＜0.05)；총주원천수LH조위(17.3±5.0)d,OH조위(21.5±5.1)d,2조비교차이유통계학의의(t=-2.717,P＜0.05).2조환자수방적총생존솔비교차이무통계학의의(x2=0.172,P ＞0.05).LH조적무류생존솔위52.4％,현저고우OH조(25.1％,x2=4.543,P＜0.05).결론 복강경여개복간절제균위간암치료적유효방법,복강경술식근기병발증소,주원시간단,단량조총체생존솔무차이.
Objective To investigate the efficiency and safety of laparoscopic hepatectomy (LH) and open hepatectomy (OH) in patients with hepatocellular carcinoma (HCC). Methods A total of 45 HCC cases undergoing hepatectomy from January 2008 to December 2010 in our hospital were divided into LH group ( n =21 ) and OH group ( n =24 ).Their clinical efficiency and safety were compared and analyzed. Results The amount of intraoperative blood loss and blood transfusion in LH group were significantly higher than that of OH ( respectively x2 =3.973,x2 =4.862,all P ＜ 0.05 ).LH is associated with less postoperative complications and duration of hospital stay,compared with OH ( respectively x2 =4.746,t =-2.717,all P ＜0.05).Cumulative survival rates in both groups were not statistically significant ( x2 =0.172,P ＞ 0.05 ).However tumor-free survival rate in LH was significantly higher,superior to that of OH (x2 =4.543,P ＜ 0.05). Conclusions LH and OH are all safe and effective hepatectomy for HCC.LH has the advantage of less complication and shorter hospital stay.