中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2012年
2期
133-136
,共4页
视神经病变%缺血性%视网膜神经纤维%光学相干
視神經病變%缺血性%視網膜神經纖維%光學相榦
시신경병변%결혈성%시망막신경섬유%광학상간
Optic Neuropathy%Ischemic%Retinal nerve fiber layer%Optical coherence
目的 探讨非动脉炎性前部缺血性视神经病变(non-arteritic anterior ischemic optic neuropathy,NAION)患眼远期视盘周围视网膜神经纤维层(retinal nerve fiber layer,RNFL)厚度及其与视野检查结果的相关性.方法 回顾性病例对照研究.对2007年8月至2009年8月在无锡市,第二人民医院眼科21例单眼发病NAION患者42只眼(21只发病眼为实验组,21只对侧正常眼为对照组)进行了视网膜神经纤维层厚度的光学相干断层扫描(optical coherence tomography,OCT),并检查视野(visual field,VF)、图形视觉诱发电位(pattern-reversal visual evoked potential,P-VEP)等检查.结果 NAION患者RNFL厚度较对照组变薄,上半侧易受累,相应下方视野缺损多见,且视盘非病变区域的RNFL厚度也比正常对照组相应区域变薄.平均RNFL厚度与视野平均缺损有相关性(r=0.38,P ＜0.05).结论 NAION患者远期盘周视神经纤维层厚度变薄,缺血区明显变薄,OCT检查非缺血区的RNFL厚度也变薄,提示NAION的RNFL丢失可能超过了视野检查的视野缺损的范围.NAION患眼盘周RNFL厚度与视野检查结果相关.
目的 探討非動脈炎性前部缺血性視神經病變(non-arteritic anterior ischemic optic neuropathy,NAION)患眼遠期視盤週圍視網膜神經纖維層(retinal nerve fiber layer,RNFL)厚度及其與視野檢查結果的相關性.方法 迴顧性病例對照研究.對2007年8月至2009年8月在無錫市,第二人民醫院眼科21例單眼髮病NAION患者42隻眼(21隻髮病眼為實驗組,21隻對側正常眼為對照組)進行瞭視網膜神經纖維層厚度的光學相榦斷層掃描(optical coherence tomography,OCT),併檢查視野(visual field,VF)、圖形視覺誘髮電位(pattern-reversal visual evoked potential,P-VEP)等檢查.結果 NAION患者RNFL厚度較對照組變薄,上半側易受纍,相應下方視野缺損多見,且視盤非病變區域的RNFL厚度也比正常對照組相應區域變薄.平均RNFL厚度與視野平均缺損有相關性(r=0.38,P ＜0.05).結論 NAION患者遠期盤週視神經纖維層厚度變薄,缺血區明顯變薄,OCT檢查非缺血區的RNFL厚度也變薄,提示NAION的RNFL丟失可能超過瞭視野檢查的視野缺損的範圍.NAION患眼盤週RNFL厚度與視野檢查結果相關.
목적 탐토비동맥염성전부결혈성시신경병변(non-arteritic anterior ischemic optic neuropathy,NAION)환안원기시반주위시망막신경섬유층(retinal nerve fiber layer,RNFL)후도급기여시야검사결과적상관성.방법 회고성병례대조연구.대2007년8월지2009년8월재무석시,제이인민의원안과21례단안발병NAION환자42지안(21지발병안위실험조,21지대측정상안위대조조)진행료시망막신경섬유층후도적광학상간단층소묘(optical coherence tomography,OCT),병검사시야(visual field,VF)、도형시각유발전위(pattern-reversal visual evoked potential,P-VEP)등검사.결과 NAION환자RNFL후도교대조조변박,상반측역수루,상응하방시야결손다견,차시반비병변구역적RNFL후도야비정상대조조상응구역변박.평균RNFL후도여시야평균결손유상관성(r=0.38,P ＜0.05).결론 NAION환자원기반주시신경섬유층후도변박,결혈구명현변박,OCT검사비결혈구적RNFL후도야변박,제시NAION적RNFL주실가능초과료시야검사적시야결손적범위.NAION환안반주RNFL후도여시야검사결과상관.
Objective To evaluate the thickness of peripapillary retinal nerve fiber layer in eyes with non-arteritic anterior ischemic optic neuropathy (NAION) and the correlation between retinal nerve fiber layer thickness with visual field detection. Methods Retrospective Case-control study.Participants:twenty-one patients diagnosed with NAION in our center between August 1 2007 and August 1 2009.Methods:Patients diagnosed with NAION were included to take optical coherence tomography scans of an area with a diameter of 3.46mm surrounding the disc and visual field and pattern-reversal visual evoked potential. Results The RNFL thickness of eyes with NAION was thinner than normal eyes,particularly in superior area,which corresponded to inferior altitudinal VF defects,and also in the unaffected area of NAION eyes.The mean RNFL thickness were correlated with visual field mean deviation (r=0.38,P ＜0.05).OCT showed that NAION eyes had marked decreased RNFL thickness at the superior sectors.And the other area RNFL thickness (corresponding to the relative unaffected visual hemi-fi eld) also showed significantly statistics lower values in NAION eyes than in control eyes. Conclusions It suggests that loss of RNFL in NAION may extend beyond the region that corresponds to the VF defect as detected.The thickness of peripapillary retinal nerve fiber layer in eyes with NAION is correlated with the visual field results.
