中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2008年
11期
1809-1810
,共2页
关节炎%类风湿%白细胞介素
關節炎%類風濕%白細胞介素
관절염%류풍습%백세포개소
Arthritis,rheumatoid%Interleukin
目的 探讨外周血白细胞介素18(IL-18)和白细胞介素17(IL-17)水平与类风湿性关节炎(RA)的相关性.方法 应用酶联免疫吸附试验(ELSIA)检测32例健康体检者和30例RA患者的IL-17和IL-18的水平.结果 健康体检者、RA患者IL-17的水平分别为(7.06±3.15)ng/rag和(25.12±11.24)ng/mg,IL-18的水平分别为(25.13±9.41)ng/mg和(151.04+21.17)ng/mg,两组IL-17、IL-18比较差异均有统计学意义(P<0.01).结论 IL-17和IL-18可能与RA免疫炎症有关.
目的 探討外週血白細胞介素18(IL-18)和白細胞介素17(IL-17)水平與類風濕性關節炎(RA)的相關性.方法 應用酶聯免疫吸附試驗(ELSIA)檢測32例健康體檢者和30例RA患者的IL-17和IL-18的水平.結果 健康體檢者、RA患者IL-17的水平分彆為(7.06±3.15)ng/rag和(25.12±11.24)ng/mg,IL-18的水平分彆為(25.13±9.41)ng/mg和(151.04+21.17)ng/mg,兩組IL-17、IL-18比較差異均有統計學意義(P<0.01).結論 IL-17和IL-18可能與RA免疫炎癥有關.
목적 탐토외주혈백세포개소18(IL-18)화백세포개소17(IL-17)수평여류풍습성관절염(RA)적상관성.방법 응용매련면역흡부시험(ELSIA)검측32례건강체검자화30례RA환자적IL-17화IL-18적수평.결과 건강체검자、RA환자IL-17적수평분별위(7.06±3.15)ng/rag화(25.12±11.24)ng/mg,IL-18적수평분별위(25.13±9.41)ng/mg화(151.04+21.17)ng/mg,량조IL-17、IL-18비교차이균유통계학의의(P<0.01).결론 IL-17화IL-18가능여RA면역염증유관.
Objective To explore the relationship between the interleukin-18 (IL-18) and interleukin-17(IL-17) levels in peripheral blood and rheumatoid arthritis(RA).Methods IL-18 and IL-17 levels were detected in 50 patients with rheumatoid arthritis and 32 heathy controls by using enzyme linked immuno-sorbent assay Results The IL-17 levels are (7.06 + 3.15)ng/mg and (25.12±11.24) ng/mg.The IL-18 levels are (25.13±9.41)ng/mg and (151.04±21.17)ng/mg in two groups.There are significant differences in them for IL-17 and IL-18 levels.Conclusion The IL-17 and IL-18 levels in peripheral blood may he associated with rheumatoid arthritis.
