CAJ | 학술논문

目的研究老年恶性肿瘤患者肠外营养相关中心静脉导管感染的发生率及危险因素.方法回顾性分析366例术后行肠外营养的老年恶性肿瘤患者的临床资料,采集患者的年龄、性别、体质量、原发疾病诊断、手术方式、既往史、输血量、输注白蛋白量、体温超过38℃天数以及肠外营养相关指标,包括肠外营养使用时间、总热能、非蛋白热能、脂肪乳剂、蛋白质和葡萄糖用量、非蛋白热能与氮比值以及糖脂比.结果 366例患者的平均年龄(71.8±6.9)岁,肠外营养时间(10.6±6.3)d,总导管留置时间3 336 d.肠外营养相关中心静脉导管感染发生率为2.5%(9/366).Logistic回归分析显示,接受肠外营养前白蛋白水平和体温升高天数与中心静脉导管感染的相对危险度分别为1.257和2.518(均P<0.01).结论老年恶性肿瘤患者接受肠外营养前白蛋白水平和体温升高天数是肠外营养相关中心静脉导管感染发生的危险因素.
목적 연구노년악성종류환자장외영양상관중심정맥도관감염적발생솔급위험인소.방법 회고성분석366례술후행장외영양적노년악성종류환자적림상자료,채집환자적년령、성별、체질량、원발질병진단、수술방식、기왕사、수혈량、수주백단백량、체온초과38℃천수이급장외영양상관지표,포괄장외영양사용시간、총열능、비단백열능、지방유제、단백질화포도당용량、비단백열능여담비치이급당지비.결과 366례환자적평균년령(71.8±6.9)세,장외영양시간(10.6±6.3)d,총도관류치시간3 336 d.장외영양상관중심정맥도관감염발생솔위2.5%(9/366).Logistic회귀분석현시,접수장외영양전백단백수평화체온승고천수여중심정맥도관감염적상대위험도분별위1.257화2.518(균P<0.01).결론 노년악성종류환자접수장외영양전백단백수평화체온승고천수시장외영양상관중심정맥도관감염발생적위험인소.
Objective To investigate the prevalence of parenteral nutrition related central venous catheter infection in elder patients with malignant tumors,and explore the risk factors. Methods The clinical data of 366 patients with malignant tumors who were managed with parenteral nutrition after operation were retrospectively analysed.The data of age,gender, body weight,diagnosis of primary disease,surgical approach,past history,volume of blood and albumin transfusion and time of fever(body temperature ≥38℃) were collected.Parenteral nutrition related parameters such as time of parenteral nutrition,total calorie,non-protein cMorie,amount of fat,protein and glucose,calorie to nitrogen ratio and carbohydrate to fat ratio were also recorded. Results The mean age of 366 patients was (71.8±6.9)years,mean time of parenteralnutrition was (10.6±6.3)d,and total time of catheterization was 3 336 days.The prevalence of parenteral nutrition related central venous catheter infection was 2.5%(9/366).Logistic regression analysis demonstrated that the relative risks of plasma albumin level before parenteral nutrition and time of high fever to catheter infection were 1.257 and 2.518,respectively(P<0.01 for both). Conclusion Plasma albumin level before parenteral nutrition and time of fever were two risk factors for parenteral nutrition related catheter infection in elder patients with malignant tumors.