CAJ | 학술논문

目的探讨肝脏慢性病毒感染对结直肠癌肝转移发生率影响,分析感染者和无感染者病例总体生存情况.方法回顾性研究2868例结直肠病例,根据外周血检测结果分为感染组和无感染组,比较两组患者肝转移发生率,分析两组患者总体生存情况及比较两组肝转移患者生存时间.结果两组病例肝转移发生率比较差异有统计学意义(P＜0.05),5年总体生存率感染组优于无感染组,肝转移伴病毒感染组中位生存期26个月,无感染组20个月,两组比较差异有统计学意义(P＜0.001).结论肝脏慢性病毒感染可降低结直肠癌肝转移发生率,有肝脏慢性病毒感染者病例总体预后优于无感染组,肝转移患者伴肝脏慢性病毒感染预后较好.
목적 탐토간장만성병독감염대결직장암간전이발생솔영향,분석감염자화무감염자병례총체생존정황.방법 회고성연구2868례결직장병례,근거외주혈검측결과분위감염조화무감염조,비교량조환자간전이발생솔,분석량조환자총체생존정황급비교량조간전이환자생존시간.결과 량조병례간전이발생솔비교차이유통계학의의(P＜0.05),5년총체생존솔감염조우우무감염조,간전이반병독감염조중위생존기26개월,무감염조20개월,량조비교차이유통계학의의(P＜0.001).결론 간장만성병독감염가강저결직장암간전이발생솔,유간장만성병독감염자병례총체예후우우무감염조,간전이환자반간장만성병독감염예후교호.
Objective To investigate the effect of chronic hepatic virus infection on colorectal cancer liver metastases,and analysis the survival between infected group and non-infected group.Methods 2868 colorectal cancer patients were retrospectively analyzed.According to the peripheral blood test,patients were divided into infected group and non-infected group.The incidence of liver metastases and survival were compared,patients with liver metastases survival time were also compared.Results Significant differences were found between two groups (P ＜ 0.05 ),5 years overall survival in infected group were better than control group.Colorectal cancer liver metastases with hepatic virus infection showed the median survival time 26 months,while the non-infected group 20 months.Conclusions Chronic hepatic virus infection decrease the risk of colorectal cancer liver metastases,also slow the better oncology outcome for these patients.Colorectal cancer liver metastases with hepatic infection show better prognosis and longer survival time.