CAJ | 학술논문

目的探索人体心脏心室肌纤维的三维结构.方法获取8例人体心脏,供者均为男性,年龄(81.9±7.2)岁,心脏质量(455.6±65.7)g.心脏放入装满水的塑料容器中,立即进行弥散张量磁共振扫描,从供者死亡到标本扫描的间隔时间为(18.6±5.2)h.扫描使用3.0 T,GE CV/Ⅰ型磁共振机进行,采用8通道线圈扫描,sshEPI和SENSE扫描序列,层厚3mm.b值1000 s/mm~2,TR 2000 ms,TE 86.4 ms.FOV 14 cm×14 cm.Voxels 128×128.Resolution1.1 mm×1.1 mm×3 mm.然后采用GE Advantage Windows workstation通过纤维追踪进行心肌纤维的可视化重建,显示并观察心肌纤维的三维结构.结果左心室前壁,室间隔,后壁及游离壁处的纤维均存在两个走行方向不同纤维层面,心内膜下层心肌纤维从基底部到心尖呈现纵斜形向下走行,中层的心肌纤维从心尖到基底部呈现横斜形向上走行,两者在心尖部呈螺旋形连接.结论人体心脏心室肌纤维的三维结构与Torrent心肌带假说所阐述的结构特征基本一致.
목적 탐색인체심장심실기섬유적삼유결구.방법 획취8례인체심장,공자균위남성,년령(81.9±7.2)세,심장질량(455.6±65.7)g.심장방입장만수적소료용기중,립즉진행미산장량자공진소묘,종공자사망도표본소묘적간격시간위(18.6±5.2)h.소묘사용3.0 T,GE CV/Ⅰ형자공진궤진행,채용8통도선권소묘,sshEPI화SENSE소묘서렬,층후3mm.b치1000 s/mm~2,TR 2000 ms,TE 86.4 ms.FOV 14 cm×14 cm.Voxels 128×128.Resolution1.1 mm×1.1 mm×3 mm.연후채용GE Advantage Windows workstation통과섬유추종진행심기섬유적가시화중건,현시병관찰심기섬유적삼유결구.결과 좌심실전벽,실간격,후벽급유리벽처적섬유균존재량개주행방향불동섬유층면,심내막하층심기섬유종기저부도심첨정현종사형향하주행,중층적심기섬유종심첨도기저부정현횡사형향상주행,량자재심첨부정라선형련접.결론인체심장심실기섬유적삼유결구여Torrent심기대가설소천술적결구특정기본일치.
Objective To study the three-dimensional structure of ventricular myocardial fiber in human heart. Methods Eight human heart were obtained from male donors aged 81.9±7.2 years with a heart weight of 455.6±65.7 g. Each sample was immersed in water and scanned by diffusion tensor magnetic resonance imaging (DT-MRI) using a 3 Tesla Exicte HD by an eight-channal head coils. The duration was 18.6±5.2 h from heart arresting to the scanning. The data were obtained using the protocol of single shot echo planarimaging (sshEPI) and sensitivity encoding (SENSE). The SENSE-sshEPI-scans (TE/TRZ86.4/2000 ms) of the whole heart were carried out (b= 1000 s/mm~2, voxels 128×128, resolution 1.1 mm×1.1 mm×3 mm, and FOV 14 cm×14 cm). Fiber tracking and reconstruction were performed using GE Advantage Windows Workstation.The three-dimensional structure of the ventricular myocardial fiber was observed. Results The left ventricular myocardial fibers showed two layers with different directions of alignment in such regions as the anterior, septum, and posterior walls and the free left ventricular wall. The subendocardial layer ran obliquely from the base to the apex, and the middle layer ran obliquely upward from the base to the apex. The two layers were linked together and aligned in the pattem ofhelical coils near the apex. Conclusions The three-dimensional structure of the myocardial fibers in human heart conforms to Torrent's hypothesis of helical ventricular myocardial band (HVMB).