中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
10期
81-83
,共3页
药物不良反应%心血管系统用药%报告分析
藥物不良反應%心血管繫統用藥%報告分析
약물불량반응%심혈관계통용약%보고분석
Adverse drug reaction%Cardiovascular drugs%Reports and analysis
目的 分析我院药物不良反应(ADR)的发生特点及影响因素,促进临床合理用药.方法 采取回顾性方法,对我院2008～2009年上报的56份ADR报告,按患者年龄、性别、给药途径、引起ADR的药物种类、涉及脏器或系统以及临床表现等进行统计、分析.结果 静脉滴注较其他给药途径更易发生ADR(51例,占91.07%);心血管系统用药引发ADR的比例最高(24例,占42.86%),其次为抗感染药物与能量、输液类药;中药注射液是引发ADR的主要心血管系统用药(15例,占26.79%).ADR的临床表现以皮疹、瘙痒等皮肤及其附件损害为主,其次为消化系统和免疫系统损害.结论 应加强药物使用的规范管理和加强ADR监测意识,完善相关报告分析制度.
目的 分析我院藥物不良反應(ADR)的髮生特點及影響因素,促進臨床閤理用藥.方法 採取迴顧性方法,對我院2008～2009年上報的56份ADR報告,按患者年齡、性彆、給藥途徑、引起ADR的藥物種類、涉及髒器或繫統以及臨床錶現等進行統計、分析.結果 靜脈滴註較其他給藥途徑更易髮生ADR(51例,佔91.07%);心血管繫統用藥引髮ADR的比例最高(24例,佔42.86%),其次為抗感染藥物與能量、輸液類藥;中藥註射液是引髮ADR的主要心血管繫統用藥(15例,佔26.79%).ADR的臨床錶現以皮疹、瘙癢等皮膚及其附件損害為主,其次為消化繫統和免疫繫統損害.結論 應加彊藥物使用的規範管理和加彊ADR鑑測意識,完善相關報告分析製度.
목적 분석아원약물불량반응(ADR)적발생특점급영향인소,촉진림상합리용약.방법 채취회고성방법,대아원2008～2009년상보적56빈ADR보고,안환자년령、성별、급약도경、인기ADR적약물충류、섭급장기혹계통이급림상표현등진행통계、분석.결과 정맥적주교기타급약도경경역발생ADR(51례,점91.07%);심혈관계통용약인발ADR적비례최고(24례,점42.86%),기차위항감염약물여능량、수액류약;중약주사액시인발ADR적주요심혈관계통용약(15례,점26.79%).ADR적림상표현이피진、소양등피부급기부건손해위주,기차위소화계통화면역계통손해.결론 응가강약물사용적규범관리화가강ADR감측의식,완선상관보고분석제도.
Objective To analyze the features and general patterns of adverse drug reactions(ADR) occurred in our hospital.Methods By a retrospective study,56 ADR cases reports collected in the hospital in 2008 ～ 2009 were analyzed statistically in respect of patients,age and sex,route of administration,category of the drugs,organs and systems involved,and clinical manifestation of the ADR.Results The ADR were more likely caused via intravenous dip(51 cases,91.07%) ;ADR was caused by cardiovascular drugs(24 cases,42.86%),secondly by antiinfection drugs and then drugs for infusing energy.Chinese pharmaceutical injecting liquids were the major of cardiovascular drugs which result in ADR( 15 cases,26.79%).The main presentation of the ADRwas damage of skin and its appendages such as erythra and pruritus etc.Besides,ADR causes the damage to digestive system and immanity system.Conclusion Great attention should be paid to standardizing the administration of using drugs,strengthening the consciousness of monitoring ADR and perfecting the regulation of analyzing related reports.
