甲状腺激素类似物的研究进展
갑상선격소유사물적연구진전
Progress in the study of thyroid hormone analogues
  • 万方数据
    中华内分泌代谢杂志 중화내분비대사잡지
    CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
    2012年 7期 599-601 ,共3页

    毛金媛%滕卫平

    모금원%등위평

    甲状腺激素类似物%甲状腺激素受体%血脂异常 甲狀腺激素類似物%甲狀腺激素受體%血脂異常
    갑상선격소유사물%갑상선격소수체%혈지이상
    Thyroid hormone analogues%Thyroid hormone receptor%Dyslipidemia
    甲状腺激素类似物是一类新兴药物,通过与甲状腺激素受体选择性结合,在特定组织中发挥拟甲状腺激素作用,尤其在降血脂和能量代谢方面.本文主要介绍了靶向特异的甲状腺激素类似物在临床前动物实验和临床试验的研究进展及应用前景.
    갑상선격소유사물시일류신흥약물,통과여갑상선격소수체선택성결합,재특정조직중발휘의갑상선격소작용,우기재강혈지화능량대사방면.본문주요개소료파향특이적갑상선격소유사물재림상전동물실험화림상시험적연구진전급응용전경.
    Thyroid hormone analogues belong to a novel class of agents,which exert thyromimetic actions by selectively binding to thyroid hormone receptors,especially in the aspects of lipid lowering and calorigenesis.This review focuses on the research and application of selective thyroid hormone analogues in animal experiments and clinical trials.
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