CAJ | 학술논문

目的调查北京地区25～54岁已婚妇女宫颈上皮内瘤变(CIN)的患病现状.方法采用横断面调查方法,于2007年3月至2008年9月,随机抽取北京地区12个区县共137个社区内25-54岁已婚妇女6339例(其中城区妇女942例,近郊区妇女3000例,远郊区妇女2397例)进行问卷调查、妇科检查、宫颈细胞涂片液基薄层细胞学检查(TCT)、宫颈分泌物高危型人乳头状瘤病毒-(HPV)检测,并对TCT结果异常者行阴道镜下宫颈活组织检查.结果 6339例妇女中,TCT结果异常者占9.58%(607/6339);病理检查诊断为CIN者占5.84%(370/6339),占TCT结果异常者的60.96%(370/607),其中CIN Ⅰ为4.65%(295/6339),CINⅡ为0.80%(51/6339),CINⅢ为0.38%(24/6339);早期浸润癌为0.06%(4/6339).城区妇女宫颈病变的患病率为4.46%(42/942),近郊区妇女为6.27%(188/3000),远郊区妇女为6.01%(144/2397),不同地区妇女宫颈病变的患病率比较,差异无统计学意义(P>0.05).结论北京地区25～54岁已婚妇女CIN的患病率为5.84%,城区与近、远郊区妇女宫颈病变患病率无差异.
목적 조사북경지구25～54세이혼부녀궁경상피내류변(CIN)적환병현상.방법 채용횡단면조사방법,우2007년3월지2008년9월,수궤추취북경지구12개구현공137개사구내25-54세이혼부녀6339례(기중성구부녀942례,근교구부녀3000례,원교구부녀2397례)진행문권조사、부과검사、궁경세포도편액기박층세포학검사(TCT)、궁경분비물고위형인유두상류병독-(HPV)검측,병대TCT결과이상자행음도경하궁경활조직검사.결과 6339례부녀중,TCT결과이상자점9.58%(607/6339);병리검사진단위CIN자점5.84%(370/6339),점TCT결과이상자적60.96%(370/607),기중CIN Ⅰ위4.65%(295/6339),CINⅡ위0.80%(51/6339),CINⅢ위0.38%(24/6339);조기침윤암위0.06%(4/6339).성구부녀궁경병변적환병솔위4.46%(42/942),근교구부녀위6.27%(188/3000),원교구부녀위6.01%(144/2397),불동지구부녀궁경병변적환병솔비교,차이무통계학의의(P>0.05).결론 북경지구25～54세이혼부녀CIN적환병솔위5.84%,성구여근、원교구부녀궁경병변환병솔무차이.
Objective To investigate prevalence of cervical intraepithelial neoplasia (CIN) among the married women aged 25-54 years in Beijing.Methods With method of cross sectional survey,6339 married women at age of 25 to 54 years were selected randomly in 137 communities of 12 districts or counties in Beijing from March 2007 to September 2008.The cervical smear cytology and high-risk human papillomavirus (HPV) infection of cervical secretion were detected.Women with abnormal cervical cytology were underwent colposcopy and cervical biopsy.Results Among 6339 women,9.58% (607/6339) cases had abnormal cytological results,the colposcopy and cervical biopsy showed the rate of CIN was 5.84% (370/6339) in total selected women and 60.96% (370/607) in women with abnormal cervical cytology,including 4.65% (295/6339) in CIN Ⅰ,0.80% (51/6339) in CIN Ⅱ,0.38% (24/6339) in CIN Ⅲ; 0.06% (4/6339)in early invasive carcinoma (SCC).Based on geographical distribution,the rate of cervical lesions was 4.46% (42/942) in urban areas,6.27% (188/3000) in suburbs and 6.01% (144/ 2397) in outer suburbs (P > 0.05).Conclusion It was found that the incidence of CIN was 5.84% in married women aged 25-54 years in Beijing,which did not show significant prevalence in urban,suburb and outer suburbs region.