CAJ | 학술논문

目的:观察艾拉光动力疗法(5-盐酸氨酮戊酸光动力疗法,5-aminolevulinie acid photodynamic therapy,ALA-PDT)治疗尖锐湿疣(Condyloma acuminatum,CA)及多发性跖疣(Verruca phmtaris,PS)的安全性与疗效.方法:以ALA-PDT治疗151例CA及PS患者,末次治疗后第1周进行疗效评价,第4、8周和12周观察复发率和不良反应.结果:疗程结束后CA及PS的疣体清除率分别为96.5%和75.4%,治疗后复发率分别为12.1%和16.3%.未发生系统不良反应,局部不良反应发生率分别为10.47%和3.08%,主要为烧灼感,局部红肿.结论:ALA-PDT治疗CA及PS治愈率均较高,但治疗CA疗效更好.复发率低,安全性好.
목적:관찰애랍광동력요법(5-염산안동무산광동력요법,5-aminolevulinie acid photodynamic therapy,ALA-PDT)치료첨예습우(Condyloma acuminatum,CA)급다발성척우(Verruca phmtaris,PS)적안전성여료효.방법:이ALA-PDT치료151례CA급PS환자,말차치료후제1주진행료효평개,제4、8주화12주관찰복발솔화불량반응.결과:료정결속후CA급PS적우체청제솔분별위96.5%화75.4%,치료후복발솔분별위12.1%화16.3%.미발생계통불량반응,국부불량반응발생솔분별위10.47%화3.08%,주요위소작감,국부홍종.결론:ALA-PDT치료CA급PS치유솔균교고,단치료CA료효경호.복발솔저,안전성호.
Objective:To research the clinical efficacy of ALA-PDT for the treatment of Condyloma Acuminatum and Verruca Plantaris.Methods:151 patients with Condyloma Acuminatum and erruca Plantaris were treated with AIA-PDT.The wart clearance rate was evalualted at the first week after the last treatment.Subsequently,the adverse reactions and recurrent ratewere observed atweeks4.8 and 12 after the treatment ended.Results:The wart clearance rates of Condyloma Acuminatum and Verruca Plantaris were 96.5%and 75.4%,the recurrent rates were 12.1% and l6.3%,respectively.There was no systemic adverse event.The adverse reactions were mild,and the incidence rates were 10.47%and 3.08%,respectively.Conclusion:ALA-PDT is a safe and effective treatment with low recurrence rate for Condyloma Acuminatum and Verruca Plantaris,especially for Condyloma Acuminatum.