中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2010年
7期
568-571
,共4页
周成会%刘纯伦%李章勇%李永强%官方勇
週成會%劉純倫%李章勇%李永彊%官方勇
주성회%류순륜%리장용%리영강%관방용
糖尿病,2型%糖尿病胃轻瘫%生物阻抗
糖尿病,2型%糖尿病胃輕癱%生物阻抗
당뇨병,2형%당뇨병위경탄%생물조항
Diabetes mellitus,type 2%Diabetic gastroparesis%Bio-impedance
目的 观察2型糖尿病患者的胃动力情况并探讨其可能的影响因素.方法 采用基于小波转换的阻抗式胃动力采集系统检测65例2型糖尿病患者及30名健康志愿者的胃动力,并检测空腹血糖(FBG)和HbA1c.结果 65例2型糖尿病患者胃动力异常的发生率为53.85%,主要胃肠症状为腹胀、早饱、嗳气.2型糖尿病患者的胃动力主功率百分比较正常对照明显降低(P<0.05).HbA1c≥6.5%组患者的胃电主功率百分比较HbA1c<6.5%组显著降低(P<0.01).老年组胃动过缓功率百分比较青、中年组均显著增高(P<0.05).FBG及病程与2型糖尿病患者的胃动力障碍无关.结论 2型糖尿病患者胃动力障碍发生率高,HbA1c≥6.5%及老年患者更易发生胃动力障碍,FBG及病程与胃动力障碍无关.
目的 觀察2型糖尿病患者的胃動力情況併探討其可能的影響因素.方法 採用基于小波轉換的阻抗式胃動力採集繫統檢測65例2型糖尿病患者及30名健康誌願者的胃動力,併檢測空腹血糖(FBG)和HbA1c.結果 65例2型糖尿病患者胃動力異常的髮生率為53.85%,主要胃腸癥狀為腹脹、早飽、噯氣.2型糖尿病患者的胃動力主功率百分比較正常對照明顯降低(P<0.05).HbA1c≥6.5%組患者的胃電主功率百分比較HbA1c<6.5%組顯著降低(P<0.01).老年組胃動過緩功率百分比較青、中年組均顯著增高(P<0.05).FBG及病程與2型糖尿病患者的胃動力障礙無關.結論 2型糖尿病患者胃動力障礙髮生率高,HbA1c≥6.5%及老年患者更易髮生胃動力障礙,FBG及病程與胃動力障礙無關.
목적 관찰2형당뇨병환자적위동력정황병탐토기가능적영향인소.방법 채용기우소파전환적조항식위동력채집계통검측65례2형당뇨병환자급30명건강지원자적위동력,병검측공복혈당(FBG)화HbA1c.결과 65례2형당뇨병환자위동력이상적발생솔위53.85%,주요위장증상위복창、조포、애기.2형당뇨병환자적위동력주공솔백분비교정상대조명현강저(P<0.05).HbA1c≥6.5%조환자적위전주공솔백분비교HbA1c<6.5%조현저강저(P<0.01).노년조위동과완공솔백분비교청、중년조균현저증고(P<0.05).FBG급병정여2형당뇨병환자적위동력장애무관.결론 2형당뇨병환자위동력장애발생솔고,HbA1c≥6.5%급노년환자경역발생위동력장애,FBG급병정여위동력장애무관.
Objective To detect the gastric motility in patients with type 2 diabetes mellitus, and to explore the relationship between disorder of gastric motility in diabetes and the influential factors. Methods Sixty-five patients with type 2 diabetes mellitus and 30 health control subjects were collected. The gastric motility was tested with the signal processing device designed by Chongqing University of Posts and Telecommunications. The impedance and electrical signals were collected at the same time. Fasting blood glucose (FBG) was detected by oxidation enzyme method, while microcolumn method was adopted to test HbA1c. Results In the 65 patients with type 2 diabetes mellitus,the occurrence of abnormal gastric motility was 53.85% , they had several symptoms, such as abdominal distension, early satiety, and belching. The percentage of dominant frequency of impedance gastrogram in diabetes group was lower than that in the normal controls (P<0. 05 ). The percentage of dominant frequency of EGG in the abnormal HbA1c group( ≥6. 5% ) was significantly lower than that in the normal HbA1c group ( P<0. 01). The percentage of bradygastria in the elderly was higher than that in young and middle-aged subjects (P<0. 05), respectively. Disorder of gastric motility was not correlated with FBG and course of disease. Conclusions The incidence of disordered gastric motility is very high in patients with type 2 diabetes mellitus. Elderly patients and those with higher HbA1c are prone to suffer from disordered gastric motility. However, disorder in gastric motility is not correlated with FBG and duration of the illness.
