中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
5期
34-36
,共3页
高胆红素血症%新生儿%酶
高膽紅素血癥%新生兒%酶
고담홍소혈증%신생인%매
Hyperbilirubinemia%Neonate%Enzyme
[目的]探讨高胆红素血症新生儿血清酶活性检测的临床意义.[方法]选择汕头市妇幼保健院新生儿科2010年7月至2011年6月收治新生儿高胆红素血症患儿120例,检测血清丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)、天门冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(γ-GT)、乳酸脱氢酶(LDH)、乳酸脱氢酶同工酶1(LDH1)、肌酸激酶(CK)和肌酸激酶同工酶(CK-MB),并与对照组(同期正常新生儿,40例)比较分析.[结果]高胆红素血症新生儿血清酶中AST、y-GT、LDH、LDHI、CK、CK-MB活性较对照组均有显著性增高,且重度组高于轻中度组,差异有统计学意义(P＜0.05);而ALT、ALP组间比较差异无统计学意义(P＞0.05).[结论]高胆红素血症新生儿血清酶活性可反映胆道排泄功能和心肌的损伤,在治疗时检测其活性变化对患儿预后判断具有重要意义.
[目的]探討高膽紅素血癥新生兒血清酶活性檢測的臨床意義.[方法]選擇汕頭市婦幼保健院新生兒科2010年7月至2011年6月收治新生兒高膽紅素血癥患兒120例,檢測血清丙氨痠氨基轉移酶(ALT)、堿性燐痠酶(ALP)、天門鼕氨痠氨基轉移酶(AST)、γ-穀氨酰轉肽酶(γ-GT)、乳痠脫氫酶(LDH)、乳痠脫氫酶同工酶1(LDH1)、肌痠激酶(CK)和肌痠激酶同工酶(CK-MB),併與對照組(同期正常新生兒,40例)比較分析.[結果]高膽紅素血癥新生兒血清酶中AST、y-GT、LDH、LDHI、CK、CK-MB活性較對照組均有顯著性增高,且重度組高于輕中度組,差異有統計學意義(P＜0.05);而ALT、ALP組間比較差異無統計學意義(P＞0.05).[結論]高膽紅素血癥新生兒血清酶活性可反映膽道排洩功能和心肌的損傷,在治療時檢測其活性變化對患兒預後判斷具有重要意義.
[목적]탐토고담홍소혈증신생인혈청매활성검측적림상의의.[방법]선택산두시부유보건원신생인과2010년7월지2011년6월수치신생인고담홍소혈증환인120례,검측혈청병안산안기전이매(ALT)、감성린산매(ALP)、천문동안산안기전이매(AST)、γ-곡안선전태매(γ-GT)、유산탈경매(LDH)、유산탈경매동공매1(LDH1)、기산격매(CK)화기산격매동공매(CK-MB),병여대조조(동기정상신생인,40례)비교분석.[결과]고담홍소혈증신생인혈청매중AST、y-GT、LDH、LDHI、CK、CK-MB활성교대조조균유현저성증고,차중도조고우경중도조,차이유통계학의의(P＜0.05);이ALT、ALP조간비교차이무통계학의의(P＞0.05).[결론]고담홍소혈증신생인혈청매활성가반영담도배설공능화심기적손상,재치료시검측기활성변화대환인예후판단구유중요의의.
[Objective]To investigate the clinical significance of seroenzyme detection in neonatal hyperbilirubinemia.[Methods]The serum enzyme of 120 cases of neonatal hyperbilirubinemia in the department of neonatology from July 2010 to June 2011 were detected,including ALT,ALP,AST,γ-GT,LDH,LDH1,CK and CK-MB.The results were compared with the control group.[Results]The activity of AST,γ-GT,LDH,LDH1,CK and CK-MB of the neonatal hyperbilirubinemia group increased significantly compared with the control group (P＜0.05),that of the severe group increased significantly than that of the mild group (P＜0.05).However,the indexes of ALT and ALP were not significantly different between the neonatal hyperbilirubinemia group and the control group (P＞0.05).[Conclusions]The detection of seroenzyme activity in neonatal hyperbilirubinemia can reflect heart injury and bile duct discharge function.Moreover,the seroenzyme detection has great significances in predicting the prognosis of neonatal hyperbilirubinemia.
