CAJ | 학술논문

从长形肉豆蔻Myristica argentea乙醇提取物乙酸乙酯部分分离得到12个化合物,经理化和波谱分析分别鉴定为黄樟醚(1)、甲基丁香酚(2)、异甲基丁香酚(3)、3'-羟基异黄樟醚(4)、7-羟基-3,4'-亚甲二氧基黄烷(5)、1,4-苯二甲酸二甲酯(6)、内消旋-二氢愈创木脂酸(7)、赤式-1-(4-羟基-3-甲氧基苯基)-4-(3,4-亚甲二氧基苯基)-2,3-二甲基丁烷(8)、赤式-1-(4-羟基-3-甲氧基苯基)-2-(2-甲氧基-4-(1(E)-丙烯基)苯氧基)-丙烷-1-醇(9)、nectandrin B(10)、β-谷甾醇(11)和胡萝卜苷(12).化合物4～6和8～12为首次自该植物中分离得到,化合物4～6为首次从该属植物中分离得到.
종장형육두구Myristica argentea을순제취물을산을지부분분리득도12개화합물,경이화화파보분석분별감정위황장미(1)、갑기정향분(2)、이갑기정향분(3)、3'-간기이황장미(4)、7-간기-3,4'-아갑이양기황완(5)、1,4-분이갑산이갑지(6)、내소선-이경유창목지산(7)、적식-1-(4-간기-3-갑양기분기)-4-(3,4-아갑이양기분기)-2,3-이갑기정완(8)、적식-1-(4-간기-3-갑양기분기)-2-(2-갑양기-4-(1(E)-병희기)분양기)-병완-1-순(9)、nectandrin B(10)、β-곡치순(11)화호라복감(12).화합물4～6화8～12위수차자해식물중분리득도,화합물4～6위수차종해속식물중분리득도.
To study the chemical constituents of Myristica argentea, chromatographic and NMR spectroscopic techniques was used to isolate and elucidate the constituents.Twelve compounds were isolated from the whole plant of Myristica argentea by silica gel column and Sephadex LH-20 chromatography and identified as safrole(1), methyleugenol(2), meth-ylisoeugenol(3), 3'-hydroxyisosafrole(4), 7-hydroxy-3', 4'-methylene-flavan(5), terephthalic acid dimethyl ester(6), erythro-1, 4-di(4-hydroxy-3-methoxyphenyl)-2, 3-dimethylbutane(meso-dihydroguaiaretic acid(7), cryhro-1-(4-hy-droxy-3-methoxyphenyl)-4-(3, 4-methylenedioxy phenyl)-2, 3-dimethyl butane(8), erythro-1-(4-hydroxy-3-methoxy-phenyl)-2-(2-methoxy-4-(1(E)-propenyl)phenoxy)-propan-1-ol(9), nectandrin B(10), β-situsterol(11), and dau-costerol(12).Compounds 4-6 and 8-12 were isolated from this plant for the first time, while compounds 4-6 and 8-12 were isolated firstly from this genus.