CAJ | 학술논문

局部晚期直肠癌单纯手术后局部复发率高,近年的随机对照Ⅲ期临床研究提示,局部晚期直肠癌的新辅助治疗可明显提高局部控制率,对于治疗后病理完全缓解者还可提高生存率,在欧美国家已成为局部晚期直肠癌的标准治疗.但化疗药物的选择、热疗等的应用等尚需进一步临床研究.
국부만기직장암단순수술후국부복발솔고,근년적수궤대조Ⅲ기림상연구제시,국부만기직장암적신보조치료가명현제고국부공제솔,대우치료후병리완전완해자환가제고생존솔,재구미국가이성위국부만기직장암적표준치료.단화료약물적선택、열료등적응용등상수진일보림상연구.
The local recurrence rote is high after operation without chemotherapy or radiotherapy for lo-cally advanced rectal cancer. Recent random-control clinical phase Ⅲ studies suggest that the neoadjuvant ther-apy for locally advanced rectal cancer can improve local control rate obviously and ameliorate survival rate for pathologically complete response patients. In Europe and America, the neoadjuvant therapy has been regarded as the standard treatment for locally advanced rectal cancer. However the choice of chemotherapy agents, the application of hyperthermia and so on will be still requested further clinical trails.