CAJ | 학술논문

目的探讨胃癌切除术后腹腔感染的影响因素.方法采用病例对照研究的方法,对1728例胃癌患者的术前状态、肿瘤病理学因素和手术方法等指标进行Logistic回归分析.结果单因素分析发现,年龄、营养不良、慢性阻塞性肺病、糖尿病、心脏病、凝血酶原时间、淋巴细胞计数、肿瘤长径、腹水、侵及周围脏器、TNM分期、胃切除方式、术中失血量、手术时间、术中输血和淋巴结清扫范围等16个因素与胃癌术后腹腔感染的发生有关;多因素分析显示,有7个独立危险因素与胃癌术后腹腔感染的发生有关,其作用由强到弱依次为:淋巴结清扫范围(N2<'+>～N3和N2)、肿瘤侵及周围脏器、糖尿病、手术时间、年龄、淋巴细胞计数.结论应针对胃癌术后IAI发生的上述主要影响因素进行必要的干预.
목적 탐토위암절제술후복강감염적영향인소.방법 채용병례대조연구적방법,대1728례위암환자적술전상태、종류병이학인소화수술방법등지표진행Logistic회귀분석.결과 단인소분석발현,년령、영양불량、만성조새성폐병、당뇨병、심장병、응혈매원시간、림파세포계수、종류장경、복수、침급주위장기、TNM분기、위절제방식、술중실혈량、수술시간、술중수혈화림파결청소범위등16개인소여위암술후복강감염적발생유관;다인소분석현시,유7개독립위험인소여위암술후복강감염적발생유관,기작용유강도약의차위:림파결청소범위(N2<'+>～N3화N2)、종류침급주위장기、당뇨병、수술시간、년령、림파세포계수.결론 응침대위암술후IAI발생적상술주요영향인소진행필요적간예.
Objective To investigate the main risk factors associated with intra-abdominal infection (IAI) following gastrectomy in gastric cancer patients. Methods Case-control study was used to investigate the clinical data of 1728 gastric carcinoma cases retrospectively by Logistic regressive analysis. Results Univariate Logistic regressive analysis showed 16 factors, including age, malnutrition, chronic obstructive pulmonary disease (COPD), diabetes mellitus (DM), heart diseases, prothrombin time, lymphocyte count, tumor size, ascites, invasion to the adjacent organ, neoplasm TNM staging (UICC, 1997), methods of gastrectomy, blood loss, operative time, blood transfusion and extent of lymph nodal dissection,were associated with postoperative intra-abdominal infection. Binary Logistic regression analysis found that extent of lymph nodal dissection(N2<'+>～N3 and N2), invasion to the adjacent organ, DM, operative time, age and lymphocyte count were the independent risk factors associated with mortality. Conclusion Necessary interventions should be carried out to prevent IAI referring to above risk factors.