CAJ | 학술논문

目的探讨定量组织运动二尖瓣环位移技术(TMAD)对心脏再同步化治疗(CRT)患者短期疗效的评价作用.方法使用TMAD技术测量26例慢性充血性心力衰竭(CHF)患者CRT前和CRT 1个月后左室壁二尖瓣环6个位点的收缩期最大位移(Ds)、二尖瓣环6个位点达峰时间的标准差(Td-sd)以及任意两位点收缩期最大位移达峰时间的最大差值(Tds-diff),并将平均Ds与简化双平面Simpson法计算的左室射血分数(LVEF)、左室收缩末容积(LVESV)及左室面积变化分数(FAC)进行相关分析.结果 CRT 1个月后二尖瓣环6个位点Ds及平均Ds比CRT前显著增高,差异有统汁学意义(P<0.01);Tds-diff较CRT前减少,差异有统汁学意义(P<0.05);二尖瓣环6个位点Td-sd较CRT、前减少,差异有统计学意义(P<0.05);二尖瓣环6个位点平均Ds与LVEF、LVESV、FAC呈正相关(r分别为0.419,0.529,0.567,P<0.05).结论 TMAD可以用来评价CRT患者的短期疗效.
목적 탐토정량조직운동이첨판배위이기술(TMAD)대심장재동보화치료(CRT)환자단기료효적평개작용.방법 사용TMAD기술측량26례만성충혈성심력쇠갈(CHF)환자CRT전화CRT 1개월후좌실벽이첨판배6개위점적수축기최대위이(Ds)、이첨판배6개위점체봉시간적표준차(Td-sd)이급임의량위점수축기최대위이체봉시간적최대차치(Tds-diff),병장평균Ds여간화쌍평면Simpson법계산적좌실사혈분수(LVEF)、좌실수축말용적(LVESV)급좌실면적변화분수(FAC)진행상관분석.결과 CRT 1개월후이첨판배6개위점Ds급평균Ds비CRT전현저증고,차이유통즙학의의(P<0.01);Tds-diff교CRT전감소,차이유통즙학의의(P<0.05);이첨판배6개위점Td-sd교CRT、전감소,차이유통계학의의(P<0.05);이첨판배6개위점평균Ds여LVEF、LVESV、FAC정정상관(r분별위0.419,0.529,0.567,P<0.05).결론 TMAD가이용래평개CRT환자적단기료효.
Objective To evaluate the tissue motion tracking of mitral annular displaeement(TMAD) method in the assessment of short-term effect of cardiac resynchronization therapy (CRT). Methods Twenty six chronic heart failure (CHF) patients with CRT were detected by TMAD. The maximal displacement of the six points of mitral annulus(DS), the standard deviation of the time to regional peak systolie displacement of the six points (Td-sd) and the maximal temporal difference of any two points(Tds-diff) were compared before and one month after CRT. And the correlation between mean displacement and left ventricular ejection fraetion(LVEF),left ventricular end systolic volume(LVESV), fraction area change (FAC) was analyzed. Results Compared with the pre-operatively, the displacement and the mean displaeement of the six points of mitral annulus were significantly increased(P<0.01),Tds diff and Td-sd were decreased(P<0.05) one month after CRT. TMAD correlated with LVEF,LVESV and FAC (r =0.419, r = 0.529, r = 0.567, P <0.05) one month after CRT. Conclusions TMAD is a new technology to evaluate the short-term effect of CRT.