CAJ | 학술논문

目的观察并分析丙种球蛋白(intravenous immune globulin,IVIG)治疗重症毛细支气管炎的疗效.方法将78例重症毛细支气管炎(Lowell评分≥10分)患儿分为治疗组40例,对照组38例,对照组给予常规综合治疗,治疗组在常规治疗的基础上给予IVIG(400 mg·kg-1·d-1)静脉滴注,每天1次,连用3 d,观察两组咳嗽、喘憋、气促、哮鸣音好转、住院时间和疗效.结果咳嗽、喘憋、气促、哮鸣音好转,住院时间,治疗组较对照组明显缩短,差异均具有统计学意义(P值均<0.05),两组临床疗效比较差异有统计学意义(U=2.475,P<0.01).结论 IVIG治疗重症毛细支气管炎疗效明显.
목적 관찰병분석병충구단백(intravenous immune globulin,IVIG)치료중증모세지기관염적료효.방법 장78례중증모세지기관염(Lowell평분≥10분)환인분위치료조40례,대조조38례,대조조급여상규종합치료,치료조재상규치료적기출상급여IVIG(400 mg·kg-1·d-1)정맥적주,매천1차,련용3 d,관찰량조해수、천별、기촉、효명음호전、주원시간화료효.결과 해수、천별、기촉、효명음호전,주원시간,치료조교대조조명현축단,차이균구유통계학의의(P치균<0.05),량조림상료효비교차이유통계학의의(U=2.475,P<0.01).결론 IVIG치료중증모세지기관염료효명현.
Objective To observe and analyze the effectiveness of using intravenous immune globulin (IVIG) in treating severe bronchiolitis. Methods Assigning 78 cases of children with severe bronchiolitis (Lowell score ≥ 10 points) into two groups. One group is treatment group with 40 cases, and the rest 38 cases form control group. Control group uses regular treatment. Treatment group adopts IVIG (400 mg·kg-1· d-1) intravenous mjectton in addition to the regular treatment, one injection a day for three consecutive days. Cough,asthma, breath shortness, wheezing sound better, the length of hospital stay, and the effect are observed in two groups. Results Treatment group showed improvement in cough, asthma, breath shortness,and wheezing sound. In terms of the length of hospital stay, treatment group was significantly shorter than control group. These differences were statistically significant (all P < 0. 05). The clinical efficacy difference between two groups was also significant (U = 2. 475, P <0.01). Conclusious The effectiveness of IVIG in treating severe bronchiolitis is significant.