CAJ | 학술논문

目的评估短暂性脑缺血发作(TIA)患者脑供血动脉的磁共振增强血管造影(CEMRA)表现.方法 55例TIA患者作为研究对象,与随机选择的同期48例正常人及46例脑梗死患者进行对比.使用GE 1.5T超导型磁共振成像系统对研究对象行CEMRA成像.分析脑供血部脑供血动脉病变与TIA的关系.结果 TIA组及正常人组以Willis环前病变为主,二者之间比较差异无统计学意义(P＜0.05);大面积脑梗死患者以Willis环后病变为主,与前二者有统计学意义(P＜0.01);三组间脑供血动脉重度狭窄及闭塞性病变的支数有统计学意义(P＜0.001),TIA组及脑梗死组供血动脉倾向于多支动脉的多发狭窄,正常人组多为单发狭窄或迂曲.结论 Willis环对脑供血具有明显的代偿作用;TIA患者脑供血动脉存在重度狭窄或闭塞性病变,可能是发生严重缺血性脑卒中的最危险因素.
목적 평고단잠성뇌결혈발작(TIA)환자뇌공혈동맥적자공진증강혈관조영(CEMRA)표현.방법 55례TIA환자작위연구대상,여수궤선택적동기48례정상인급46례뇌경사환자진행대비.사용GE 1.5T초도형자공진성상계통대연구대상행CEMRA성상.분석뇌공혈부뇌공혈동맥병변여TIA적관계.결과 TIA조급정상인조이Willis배전병변위주,이자지간비교차이무통계학의의(P＜0.05);대면적뇌경사환자이Willis배후병변위주,여전이자유통계학의의(P＜0.01);삼조간뇌공혈동맥중도협착급폐새성병변적지수유통계학의의(P＜0.001),TIA조급뇌경사조공혈동맥경향우다지동맥적다발협착,정상인조다위단발협착혹우곡.결론 Willis배대뇌공혈구유명현적대상작용;TIA환자뇌공혈동맥존재중도협착혹폐새성병변,가능시발생엄중결혈성뇌졸중적최위험인소.
Objective To evaluate the brain feeding arteries in the patients with transient isehemic attacks(TIA) with contrast enhancement magnetic resonance angiography(MRA).Methods 55 TIA patients were chosen as study subjects,and 48 normal subjects and 46 patients with large area brain infarctions were randomly chosen as control subjects.CEMRA was performed with a superconductive GE 1.5T system.The relationship between TIA and the degree of stenosis of brain feeding arteries were analyzed.Results More lesions were found before the Circle of Willis in normal subjects and the TIA patients,and there were no significant difference between the to groups(P=0.729);More lesions were found behind the Circle of Wims in the patients with brain infarctions,and there were significant difference compared with the former two groups(P＜0.001).There were significant difference among the three groups on the number and the degree of stenosis of the brain feeding artery(P=0.006).TIA and brain infarctions were more prone to have multiple lesions.Conclusion The Circle of Willis had significant compensation for the brain blood-supply.Stenosis or occlusions of brain feeding arteries in patients with TIA might be the risk factors for severe ischemia stroke occurring.