中国医学影像技术
中國醫學影像技術
중국의학영상기술
CHINESE JOURNAL OF MEDICAL IMAGING TECHNOLOGY
2010年
1期
89-92
,共4页
卞读军%肖恩华%胡冬煦%肖运平%陈翔宇%司徒卫军%贺忠%袁术文%孙剑宁
卞讀軍%肖恩華%鬍鼕煦%肖運平%陳翔宇%司徒衛軍%賀忠%袁術文%孫劍寧
변독군%초은화%호동후%초운평%진상우%사도위군%하충%원술문%손검저
磁共振成像%灌注成像%癌,肝细胞的%经导管动脉化疗栓塞
磁共振成像%灌註成像%癌,肝細胞的%經導管動脈化療栓塞
자공진성상%관주성상%암,간세포적%경도관동맥화료전새
Magnetic resonance imaging%Perfusion imaging%Carcinoma,hepatocellular%Transcatheter arterial chemoembolization
目的 观察肝细胞癌(HCC)患者经导管动脉化疗栓塞(TACE)治疗前后磁共振灌注加权成像(MR PWI)灌注值改变.方法 对22例HCC患者在TACE术前和术后3～10天分别进行MR PWI,得出术前及术后平均强化时间(MTE)、负增强积分(NEI)、病灶达峰值时间(TTP)、最大信号下降斜率 (MSD),比较TACE术前与术后上述各指标的差异.结果 HCC瘤区时间信号曲线(TIC)TACE术前呈快速下降,TACE术后趋向平缓;MTE与TTP值术后较术前降低,NEI值术后较术前升高,差异均有统计学意义(P<0.05);MSD值术后较术前降低,但差异无统计学意义(P>0.05).结论 MR PWI能够敏感地观察到HCC TACE术前后的血流变化,可用于评价TACE疗效.
目的 觀察肝細胞癌(HCC)患者經導管動脈化療栓塞(TACE)治療前後磁共振灌註加權成像(MR PWI)灌註值改變.方法 對22例HCC患者在TACE術前和術後3～10天分彆進行MR PWI,得齣術前及術後平均彊化時間(MTE)、負增彊積分(NEI)、病竈達峰值時間(TTP)、最大信號下降斜率 (MSD),比較TACE術前與術後上述各指標的差異.結果 HCC瘤區時間信號麯線(TIC)TACE術前呈快速下降,TACE術後趨嚮平緩;MTE與TTP值術後較術前降低,NEI值術後較術前升高,差異均有統計學意義(P<0.05);MSD值術後較術前降低,但差異無統計學意義(P>0.05).結論 MR PWI能夠敏感地觀察到HCC TACE術前後的血流變化,可用于評價TACE療效.
목적 관찰간세포암(HCC)환자경도관동맥화료전새(TACE)치료전후자공진관주가권성상(MR PWI)관주치개변.방법 대22례HCC환자재TACE술전화술후3～10천분별진행MR PWI,득출술전급술후평균강화시간(MTE)、부증강적분(NEI)、병조체봉치시간(TTP)、최대신호하강사솔 (MSD),비교TACE술전여술후상술각지표적차이.결과 HCC류구시간신호곡선(TIC)TACE술전정쾌속하강,TACE술후추향평완;MTE여TTP치술후교술전강저,NEI치술후교술전승고,차이균유통계학의의(P<0.05);MSD치술후교술전강저,단차이무통계학의의(P>0.05).결론 MR PWI능구민감지관찰도HCC TACE술전후적혈류변화,가용우평개TACE료효.
Objective To observe the change of MR perfusion value in patients with hepatocellular carcinoma (HCC) before and after transcatheter arterial chemoembolization (TACE). Methods A total of 22 patients with HCC underwent MR perfusion weighted imaging (MR PWI) before TACE and 3-10 days after TACE. The mean time to enhance (MTE), negative enhancement integral (NEI), time to peak (TTP) and maximum slope of decrease (MSD) before and after TACE were acquired and compared. Results The time intension curve (TIC) of HCC region was observed to descend rapidly before TACE, while descended slowly after TACE. The value of MTE and TTP after TACE were lower than those before TACE (P<0.05), and the value of NEI after TACE was higher than that before TACE (P<0.05). The value of MSD after TACE were lower than that before TACE, but no statistical significance was found (P>0.05). Conclusion MR PWI is a very sensitive imaging technique that be used to monitor blood flow changes of HCC before and after TACE and evaluate efficacy of TACE.
