CAJ | 학술논문

目的研究玉米粗多糖的主要糖苷键结构及其对小鼠免疫调节功能的影响.方法用热水抽提法和沉淀复溶法提取、分离、纯化玉米粗多糖,根据玉米粗多糖的理化性质及波谱数据鉴定其结构:采用免疫药理学实验评价玉米粗多糖的生物活性.结果分离得到的玉米粗多糖具有与米糠多糖一致的化学结构,为一种以α-1,4和α-1,6糖苷键形式结合的葡聚糖:玉米粗多糖多项免疫药理学指标表明其具有显著的生物活性.结论首次从玉米种子中分离鉴定了玉米粗多糖,其对小鼠免疫功能具有显著的调节作用.
목적 연구옥미조다당적주요당감건결구급기대소서면역조절공능적영향.방법 용열수추제법화침정복용법제취、분리、순화옥미조다당,근거옥미조다당적이화성질급파보수거감정기결구:채용면역약이학실험평개옥미조다당적생물활성.결과 분리득도적옥미조다당구유여미강다당일치적화학결구,위일충이α-1,4화α-1,6당감건형식결합적포취당:옥미조다당다항면역약이학지표표명기구유현저적생물활성.결론 수차종옥미충자중분리감정료옥미조다당,기대소서면역공능구유현저적조절작용.
Objective To investigate the glycosidic linkage and immunomodulating activities of crude polysaccharides from the seeds of Zea mays. Methods Extraction, isolation and purification of polysaccharides were carried out with boiling-water extraction plus resolving deposit repeatedly. The structure was elucidated on basis of physicochemical properties and spectral data, and the biological activities were evaluated by means of Immunopharmacological examination. Results The structure of polysaccharides from the seeds of Z. mays exhibited identical structure with rice bran polysaccharides, i.e., a kind of glucan withα-1,4 andα-1,6 glucosidic bonds as the main frame. Conclusion Polysaccharides was obtained from the seeds of Z. mays for the first time, and it showed significant immunomodulating activity in mice.