国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2008年
8期
615-619
,共5页
C-反应蛋白%脑梗死%基因多态性%动脉粥样硬化%炎症
C-反應蛋白%腦梗死%基因多態性%動脈粥樣硬化%炎癥
C-반응단백%뇌경사%기인다태성%동맥죽양경화%염증
C-reactive protein%brain infarction,gene polymorphism%atherosclerosis%inflammation
C-反应蛋白(CRP)是最敏感的急相蛋白指标.越来越多的证据表明,作为脑梗死的主要病因,动脉粥样硬化是一种慢性炎症过程.目前的研究发现,CRP水平及基因多态性与动脉粥样硬化和脑梗死有关.与冠心病相比,超敏CRP与缺血性卒中的关联性更为紧密.文章就CRP的生物学特征、影响CRP水平的因素、CRP水平和基因多态性与脑梗死的相关性的研究进展做了综述.
C-反應蛋白(CRP)是最敏感的急相蛋白指標.越來越多的證據錶明,作為腦梗死的主要病因,動脈粥樣硬化是一種慢性炎癥過程.目前的研究髮現,CRP水平及基因多態性與動脈粥樣硬化和腦梗死有關.與冠心病相比,超敏CRP與缺血性卒中的關聯性更為緊密.文章就CRP的生物學特徵、影響CRP水平的因素、CRP水平和基因多態性與腦梗死的相關性的研究進展做瞭綜述.
C-반응단백(CRP)시최민감적급상단백지표.월래월다적증거표명,작위뇌경사적주요병인,동맥죽양경화시일충만성염증과정.목전적연구발현,CRP수평급기인다태성여동맥죽양경화화뇌경사유관.여관심병상비,초민CRP여결혈성졸중적관련성경위긴밀.문장취CRP적생물학특정、영향CRP수평적인소、CRP수평화기인다태성여뇌경사적상관성적연구진전주료종술.
C-reactive protein(CRP)is the most sensitive indicator of acute phase proteins.A growing body of evidence suggests that atherosclerosis,as a main cause of cerebral infarction,is a chronic inflammtory process.The present studies have found that the CRP levels and genetic polymorphisms are associated with atherosclerosis and cerebral infarction.As compared with coronary artery disease,the association between high-sensitive CRP and ischemic stroke is more closely.This article reviews the advaces in research on the biological characteristics of CRP,the factors influencing CRP levels,the CRP levels and the correlation between genetic polymorphisms and cerebral infarction.
