CAJ | 학술논문

目的探索一种操作简单、疗效显著、医护人员及病人乐于接受的预防和治疗化疗性静脉炎的方法.方法将使用环磷酰胺、5-氟脲嘧啶、表阿霉素化疗的住院病人随机分为实验组与对照组:实验组40例应用喜辽妥软膏在穿刺处周围并沿血管走向涂抹10～15 cm,每天2次.每次化疗后继续涂抹3天;对照组41例则按传统静脉炎处理方法,用50%硫酸镁湿敷,每天2次,每次化疗后继续涂抹3天.结果两组病人静脉炎发生率分别为22.50%,67.29%(P<0.05).发生的静脉炎分级比较,疼痛缓解时间和炎症消除时间实验组均低于对照组,差异有显著性(P<0.05).结论喜辽妥软膏局部涂抹能有效减少环磷酰胺、5-氟脲嘧啶、表阿霉素所致的化学性静脉炎的发生,减轻静脉炎发生的程度,保证了化疗的正常进行,值得推广应用.
목적 탐색일충조작간단、료효현저、의호인원급병인악우접수적예방화치료화료성정맥염적방법.방법 장사용배린선알、5-불뇨밀정、표아매소화료적주원병인수궤분위실험조여대조조:실험조40례응용희료타연고재천자처주위병연혈관주향도말10～15 cm,매천2차.매차화료후계속도말3천;대조조41례칙안전통정맥염처리방법,용50%류산미습부,매천2차,매차화료후계속도말3천.결과 량조병인정맥염발생솔분별위22.50%,67.29%(P<0.05).발생적정맥염분급비교,동통완해시간화염증소제시간실험조균저우대조조,차이유현저성(P<0.05).결론 희료타연고국부도말능유효감소배린선알、5-불뇨밀정、표아매소소치적화학성정맥염적발생,감경정맥염발생적정도,보증료화료적정상진행,치득추엄응용.
Objective To explore a simple, effective therapy in the prevention and treatment of chemotherapy-induced phlebitis which medical staff and patients are all willing to use. Methods 81 patients who received chemotherapy with cyclophosphamide, 5-fluorouracil, and pharmorubicin were randomly divided into two groups:study group ( n = 40 ) and control group ( n = 41 ). In the study group, hirudoid was applied around the puncture point and along the direction of the vessel of 10 - 15cm, twice daily for three days after the start of chemotherapy. The control group received traditional therapy for phlebitis - wet dressing with 50% magnesium sulfate, twice daily for three days. Results The incidence of phlebitis was 22.50% in hirudoid group and 67.29% in magnesium sulfate group ( P< 0.05 ). The time of pain-relief and that of inflammation elimination were shorter in the study group than in the control group ( P < 0.05 ). Conclusions Topical hirudoid can effectively reduce the incidence rate of cyclophosphamide-, 5-fluorouracil-, and pharmorubicin-induced phlebitis, reduce the degree of phlebitis, and ensure the process of chemotherapy. It is worth popularizing.