应用化工
應用化工
응용화공
APPLIED CHEMICAL INDUSTRY
2009年
12期
1742-1745
,共4页
洪正源%郭嘉%袁军%池汝安%费斌
洪正源%郭嘉%袁軍%池汝安%費斌
홍정원%곽가%원군%지여안%비빈
活性炭%维生素B_3%维生素C%吸附%缓释
活性炭%維生素B_3%維生素C%吸附%緩釋
활성탄%유생소B_3%유생소C%흡부%완석
activated carbon%vitamin B_3%vitamin C%adsorption%controlled release
研究活性炭吸附维生素B_3和维生素C以及在模拟体内环境中的释放过程.探讨了活性炭孔结构对吸附维生素B_3和维生素C的影响,并对活性炭缓释维生素B_3过程进行了数学模拟,初步探讨了吸附和释放机制.实验所用活性炭对维生素B_3有较强吸附能力,吸附量达到了94.9 mg/g,对维生素C的吸附量仅38.5 mg/g.采用活性炭对维生素B3有良好的缓释性能,其整个释放过程符合药物体外释放一级动力学模型为Q=38.25-36.90e~(-0.049 24t).所用活性炭适于作为缓释维生素B3的载体,而由于维生素C的不稳定性,不适宜使用活性炭缓释.
研究活性炭吸附維生素B_3和維生素C以及在模擬體內環境中的釋放過程.探討瞭活性炭孔結構對吸附維生素B_3和維生素C的影響,併對活性炭緩釋維生素B_3過程進行瞭數學模擬,初步探討瞭吸附和釋放機製.實驗所用活性炭對維生素B_3有較彊吸附能力,吸附量達到瞭94.9 mg/g,對維生素C的吸附量僅38.5 mg/g.採用活性炭對維生素B3有良好的緩釋性能,其整箇釋放過程符閤藥物體外釋放一級動力學模型為Q=38.25-36.90e~(-0.049 24t).所用活性炭適于作為緩釋維生素B3的載體,而由于維生素C的不穩定性,不適宜使用活性炭緩釋.
연구활성탄흡부유생소B_3화유생소C이급재모의체내배경중적석방과정.탐토료활성탄공결구대흡부유생소B_3화유생소C적영향,병대활성탄완석유생소B_3과정진행료수학모의,초보탐토료흡부화석방궤제.실험소용활성탄대유생소B_3유교강흡부능력,흡부량체도료94.9 mg/g,대유생소C적흡부량부38.5 mg/g.채용활성탄대유생소B3유량호적완석성능,기정개석방과정부합약물체외석방일급동역학모형위Q=38.25-36.90e~(-0.049 24t).소용활성탄괄우작위완석유생소B3적재체,이유우유생소C적불은정성,불괄의사용활성탄완석.
Adsorption of vitamin B_3 and vitamin C by activated carbons and their controlled release were investigated in this paper.The effect of pore structure of the activated carbon on the adsorption of vitamin B_3 and vitamin C was studied.The process of vitamin B_3 release was simulated and the mechanism for adsorption and release was also discussed.The activated carbon possessed high adsorptive capacity for vitamin B_3,with the amount of 94.9 mg/g,but the value for vitamin C was only 38.5 mg/g.The release process was marched with first-order kinetic model Q=38.25-36.90e~(-0.049 24t).The activated carbon might be used as the carrier for vitamin B_3 release, but not suitable for vitamin C due to its instability.